Occupational asthma due to formaldehyde

Cheol Woo Kim, Jae Seok Song, Yeon Soon Ahn, Seung Hyun Park, Jung Won Park, Jae Hoon Noh, Chein Soo Hong

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Formaldehyde is a low molecular weight chemical and can elicit acute and chronic health related problems. Most of the inhaled formaldehyde is retained in the upper respiratory tract due to its extraordinary solubility. Therefore, cases of formal-dehyde-induced occupational asthma are sporadic despite its widespread use in industrial processes. We herein report upon a case of occupational asthma due to formaldehyde, which was confirmed by workplace challenge including working environmental assessments, and by formaldehyde inhalation challenge using a specially designed closed-circuit apparatus. To investigate the possible involvement of an IgE-mediated mechanism, both in vitro and in vivo tests were done. IgE antibody specific for formaldehyde-human serum albumin conjugate (F-HSA) was not detected by ELISA, and no specific cutaneous reactivity to F-HSA was noted by either skin prick or intradermal test. The patient was diagnosed with formaldehyde-induced occupational asthma not associated with an IgE mediated mechanism.

Original languageEnglish
Pages (from-to)440-445
Number of pages6
JournalYonsei medical journal
Volume42
Issue number4
DOIs
Publication statusPublished - 2001 Jan 1

Fingerprint

Occupational Asthma
Formaldehyde
Immunoglobulin E
Intradermal Tests
Skin Tests
Workplace
Respiratory System
Solubility
Inhalation
Molecular Weight
Enzyme-Linked Immunosorbent Assay
Skin
Antibodies
Health

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kim, C. W., Song, J. S., Ahn, Y. S., Park, S. H., Park, J. W., Noh, J. H., & Hong, C. S. (2001). Occupational asthma due to formaldehyde. Yonsei medical journal, 42(4), 440-445. https://doi.org/10.3349/ymj.2001.42.4.440
Kim, Cheol Woo ; Song, Jae Seok ; Ahn, Yeon Soon ; Park, Seung Hyun ; Park, Jung Won ; Noh, Jae Hoon ; Hong, Chein Soo. / Occupational asthma due to formaldehyde. In: Yonsei medical journal. 2001 ; Vol. 42, No. 4. pp. 440-445.
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Kim, CW, Song, JS, Ahn, YS, Park, SH, Park, JW, Noh, JH & Hong, CS 2001, 'Occupational asthma due to formaldehyde', Yonsei medical journal, vol. 42, no. 4, pp. 440-445. https://doi.org/10.3349/ymj.2001.42.4.440

Occupational asthma due to formaldehyde. / Kim, Cheol Woo; Song, Jae Seok; Ahn, Yeon Soon; Park, Seung Hyun; Park, Jung Won; Noh, Jae Hoon; Hong, Chein Soo.

In: Yonsei medical journal, Vol. 42, No. 4, 01.01.2001, p. 440-445.

Research output: Contribution to journalArticle

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Kim CW, Song JS, Ahn YS, Park SH, Park JW, Noh JH et al. Occupational asthma due to formaldehyde. Yonsei medical journal. 2001 Jan 1;42(4):440-445. https://doi.org/10.3349/ymj.2001.42.4.440