Odontogenic ghost cell tumour with clear cell components: Clear cell odontogenic ghost cell tumour?

Jung Hoon Yoon, Sang Gun Ahn, Su Gwan Kim, Jin Kim

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A case of odontogenic ghost cell tumour (OGCT) with clear cell components was encountered in the mandible of a 63-year-old man. The tumour revealed ameloblastomatous-type epithelial components accompanied by clusters of ghost cells and dentinoid juxtaposed to the odontogenic epithelium. In addition, some areas of the tumour tissue showed sheets and islands of clear, glycogen containing epithelial cells, which were separated by a thin fibrous connective tissue stroma. Both ameloblastic and clear cells exhibited positive immunoreactivities for cytokeratin 19 and AE1/3. It is not known whether this tumour represents a clear cell change of a pre-existing OGCT or a separate and distinct neoplasm derived de novo from the odontogenic epithelium. This tumour was given the term 'clear cell OGCT' because it captures the clear cell components, which is one of the most prominent distinguishing features of the tumour.

Original languageEnglish
Pages (from-to)376-379
Number of pages4
JournalJournal of Oral Pathology and Medicine
Volume33
Issue number6
Publication statusPublished - 2004 Jul 1

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Cellular Structures
Neoplasms
Epithelium
Keratin-19
Glycogen
Mandible
Islands
Connective Tissue
Epithelial Cells

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Oral Surgery
  • Otorhinolaryngology
  • Cancer Research
  • Periodontics

Cite this

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abstract = "A case of odontogenic ghost cell tumour (OGCT) with clear cell components was encountered in the mandible of a 63-year-old man. The tumour revealed ameloblastomatous-type epithelial components accompanied by clusters of ghost cells and dentinoid juxtaposed to the odontogenic epithelium. In addition, some areas of the tumour tissue showed sheets and islands of clear, glycogen containing epithelial cells, which were separated by a thin fibrous connective tissue stroma. Both ameloblastic and clear cells exhibited positive immunoreactivities for cytokeratin 19 and AE1/3. It is not known whether this tumour represents a clear cell change of a pre-existing OGCT or a separate and distinct neoplasm derived de novo from the odontogenic epithelium. This tumour was given the term 'clear cell OGCT' because it captures the clear cell components, which is one of the most prominent distinguishing features of the tumour.",
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Odontogenic ghost cell tumour with clear cell components : Clear cell odontogenic ghost cell tumour? / Yoon, Jung Hoon; Ahn, Sang Gun; Kim, Su Gwan; Kim, Jin.

In: Journal of Oral Pathology and Medicine, Vol. 33, No. 6, 01.07.2004, p. 376-379.

Research output: Contribution to journalArticle

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