Oil droplet generation in PDMS microchannel using an amphiphilic continuous phase

Su Kyoung Chae, Chang Ha Lee, Soo Hyun Lee, Tae Song Kim, Ji Yoon Kang

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


This paper reports an amphiphilic solution can be used as a new continuous phase to generate double droplet emulsions (water/oil/IPA) with neither surface treatment nor surfactant in PDMS microfluidic chip. The affinity of various amphiphilic solutions in the microchannel was influenced by the polarity ratio and the size of molecules. The polarity ratio of isopropyl alcohol (IPA) was closest to that of the recovered PDMS surface and the chain length of IPA was also suitable for high affinity. IPA showed the highest affinity for the recovered PDMS and was selected as the continuous phase to form oil droplets in a PDMS microchannel. With this new continuous phase solution, IPA, we could successfully generate not only oil droplets but also double emulsions in the PDMS microfluidic chips.

Original languageEnglish
Pages (from-to)1957-1961
Number of pages5
JournalLab on a chip
Issue number13
Publication statusPublished - 2009

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering


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