On-demand drug release system for in vivo cancer treatment through self-assembled magnetic nanoparticles

Jae Hyun Lee; Kuan Ju Chen; Seung Hyun Noh; Mitch André Garcia; Hao Wang; Wei Yu Lin; Heeyeong Jeong; Brian Junoh Kong; David B. Stout; Jinwoo Cheon; Hsian Rong Tseng

doi:10.1002/anie.201207721

On-demand drug release system for in vivo cancer treatment through self-assembled magnetic nanoparticles

Jae Hyun Lee, Kuan Ju Chen, Seung Hyun Noh, Mitch André Garcia, Hao Wang, Wei Yu Lin, Heeyeong Jeong, Brian Junoh Kong, David B. Stout, Jinwoo Cheon, Hsian Rong Tseng

Research output: Contribution to journal › Article › peer-review

175 Citations (Scopus)

Abstract

On-demand drug release: Magnetothermally responsive drug-encapsulated supramolecular nanoparticles for on-demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.

Original language	English
Pages (from-to)	4384-4388
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	16
DOIs	https://doi.org/10.1002/anie.201207721
Publication status	Published - 2013 Apr 15

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/anie.201207721

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abstract = "On-demand drug release: Magnetothermally responsive drug-encapsulated supramolecular nanoparticles for on-demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.",

author = "Lee, {Jae Hyun} and Chen, {Kuan Ju} and Noh, {Seung Hyun} and Garcia, {Mitch Andr{\'e}} and Hao Wang and Lin, {Wei Yu} and Heeyeong Jeong and Kong, {Brian Junoh} and Stout, {David B.} and Jinwoo Cheon and Tseng, {Hsian Rong}",

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AU - Lee, Jae Hyun

AU - Chen, Kuan Ju

AU - Noh, Seung Hyun

AU - Garcia, Mitch André

AU - Wang, Hao

AU - Lin, Wei Yu

AU - Jeong, Heeyeong

AU - Kong, Brian Junoh

AU - Stout, David B.

AU - Cheon, Jinwoo

AU - Tseng, Hsian Rong

PY - 2013/4/15

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On-demand drug release system for in vivo cancer treatment through self-assembled magnetic nanoparticles

Abstract

All Science Journal Classification (ASJC) codes

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