Oncologic and functional outcomes of salvage supracricoid partial laryngectomy

Ji Hoon Kim, Won Shik Kim, Yoonwoo Koh, Se Heon Kim, Hyung Kwon Byeon, Eun Chang Choi

Research output: Contribution to journalArticle

Abstract

Background: Supracricoid partial laryngectomy (SCL) can have a positive impact on patients’ quality of life by circumventing dysphagia and voice problems resulting from creation of a permanent stoma after conventional total laryngectomy (TL) surgery. Aims/Objectives: The aim of this study was to investigate the oncologic and functional outcomes of salvage SCL for recurrent laryngeal carcinoma. Material and methods: Forty-five patients that underwent salvage surgery for recurrent laryngeal carcinoma between January 2004 and May 2015 after initial treatment failure were included in this retrospective study. Results: Overall survival and disease free survival were non-significantly higher in the salvage SCL group (n = 14) than in the salvage TL group (n = 31) (87.5 versus 56.5%, 53.4 versus 41.9%). Multivariate analyses showed only positive resection margin to be significantly associated with survival and recurrence (HR 9.974, p =.007, and HR 9.196, p =.002, respectively). In the salvage SCL group, 92.8% achieved successful decannulation and all patients returned to an oral diet. All patients in the salvage TL group sustained a permanent stoma and conversation was possible only through esophageal voice or a voice prosthesis. 74.2% of patients in the group were able to tolerate an oral diet. Conclusions and significance: Salvage SCL showed comparable oncologic outcomes and favorable functional outcomes relative to the classic salvage TL. This study could provide a sufficient basis of SCL as salvage treatment for recurrent laryngeal carcinoma in selected patients.

Original languageEnglish
Pages (from-to)1117-1122
Number of pages6
JournalActa Oto-Laryngologica
Volume138
Issue number12
DOIs
Publication statusPublished - 2018 Dec 2

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Laryngectomy
Carcinoma
Artificial Larynges
Diet
Salvage Therapy
Survival
Deglutition Disorders
Treatment Failure
Disease-Free Survival
Multivariate Analysis
Retrospective Studies
Quality of Life
Recurrence

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Kim, Ji Hoon ; Kim, Won Shik ; Koh, Yoonwoo ; Kim, Se Heon ; Byeon, Hyung Kwon ; Choi, Eun Chang. / Oncologic and functional outcomes of salvage supracricoid partial laryngectomy. In: Acta Oto-Laryngologica. 2018 ; Vol. 138, No. 12. pp. 1117-1122.
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abstract = "Background: Supracricoid partial laryngectomy (SCL) can have a positive impact on patients’ quality of life by circumventing dysphagia and voice problems resulting from creation of a permanent stoma after conventional total laryngectomy (TL) surgery. Aims/Objectives: The aim of this study was to investigate the oncologic and functional outcomes of salvage SCL for recurrent laryngeal carcinoma. Material and methods: Forty-five patients that underwent salvage surgery for recurrent laryngeal carcinoma between January 2004 and May 2015 after initial treatment failure were included in this retrospective study. Results: Overall survival and disease free survival were non-significantly higher in the salvage SCL group (n = 14) than in the salvage TL group (n = 31) (87.5 versus 56.5{\%}, 53.4 versus 41.9{\%}). Multivariate analyses showed only positive resection margin to be significantly associated with survival and recurrence (HR 9.974, p =.007, and HR 9.196, p =.002, respectively). In the salvage SCL group, 92.8{\%} achieved successful decannulation and all patients returned to an oral diet. All patients in the salvage TL group sustained a permanent stoma and conversation was possible only through esophageal voice or a voice prosthesis. 74.2{\%} of patients in the group were able to tolerate an oral diet. Conclusions and significance: Salvage SCL showed comparable oncologic outcomes and favorable functional outcomes relative to the classic salvage TL. This study could provide a sufficient basis of SCL as salvage treatment for recurrent laryngeal carcinoma in selected patients.",
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Oncologic and functional outcomes of salvage supracricoid partial laryngectomy. / Kim, Ji Hoon; Kim, Won Shik; Koh, Yoonwoo; Kim, Se Heon; Byeon, Hyung Kwon; Choi, Eun Chang.

In: Acta Oto-Laryngologica, Vol. 138, No. 12, 02.12.2018, p. 1117-1122.

Research output: Contribution to journalArticle

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T1 - Oncologic and functional outcomes of salvage supracricoid partial laryngectomy

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AU - Kim, Won Shik

AU - Koh, Yoonwoo

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AU - Byeon, Hyung Kwon

AU - Choi, Eun Chang

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