One-pot access to 2-amino-3-arylbenzofurans: Direct entry to polyheterocyclic chemical space

Sure Siva Prasad, Dirgha Raj Joshi, Jeong Hwa Lee, Ikyon Kim

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

As a means to make new benzofuran-embedded polycyclic structures, we established two efficient one-pot sequential coupling routes to 2-amino-3-arylbenzofurans and 2-amino-3-arylnaphtho[2,1-b]furans. Further ring formation (six- and seven-membered rings) with the resulting amine moiety at the C2 position of benzofurans was realized, leading to further expansion of benzofuran-based chemical space.

Original languageEnglish
Pages (from-to)8119-8140
Number of pages22
JournalOrganic and Biomolecular Chemistry
Volume18
Issue number40
DOIs
Publication statusPublished - 2020 Oct 28

Bibliographical note

Funding Information:
We thank the National Research Foundation of Korea (NRF-2018R1A6A1A03023718 and NRF-2020R1A2C2005961) for generous financial support.

Publisher Copyright:
© The Royal Society of Chemistry.

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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