One-pot catalytic C-C double bond cleavage of α,β-enones aided by alkyl group-immobilized silica spheres

Dong Hun Lee, Eun Ae Jo, Jung Woo Park, Chul Ho Jun

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Catalytic C-C double bond cleavage of α,β-enones with a 1-alkene and H2O was carried out in the presence of a (Ph3P)3RhCl catalyst, 2-amino-3-picoline, cyclohexylamine, benzoic acid, and alkyl group-immobilized silica spheres. Upon completion of the reaction, the corresponding ketones were obtained without needing a further hydrolysis step. In this reaction, alkyl group-immobilized silica spheres act as a water reservoir for hydrolysis of an intermediate ketimine and as a phase divider between the organic solution and H2O.

Original languageEnglish
Pages (from-to)160-163
Number of pages4
JournalTetrahedron Letters
Volume51
Issue number1
DOIs
Publication statusPublished - 2010 Jan 6

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'One-pot catalytic C-C double bond cleavage of α,β-enones aided by alkyl group-immobilized silica spheres'. Together they form a unique fingerprint.

  • Cite this