One-pot, three-component approach to diarylacetonitriles

Dileep Kumar Singh, Sure Siva Prasad, Jinhwang Kim, Ikyon Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Described herein is a novel one-pot, three-component reaction where aldehydes, electron-rich arenes, and TMSCN in the presence of BF 3 -OEt 2 allowed direct access to a number of diarylacetonitriles under mild reaction conditions in good to excellent yields. Implementation of this assembly protocol to a concise synthetic approach to shoreaphenol, a bioactive oligostilbenoid natural product, is also demonstrated.

Original languageEnglish
Pages (from-to)669-673
Number of pages5
JournalOrganic Chemistry Frontiers
Volume6
Issue number5
DOIs
Publication statusPublished - 2019 Mar 7

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Biological Products
Aldehydes
Electrons
trimethylsilyl cyanide

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

Singh, Dileep Kumar ; Prasad, Sure Siva ; Kim, Jinhwang ; Kim, Ikyon. / One-pot, three-component approach to diarylacetonitriles. In: Organic Chemistry Frontiers. 2019 ; Vol. 6, No. 5. pp. 669-673.
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One-pot, three-component approach to diarylacetonitriles. / Singh, Dileep Kumar; Prasad, Sure Siva; Kim, Jinhwang; Kim, Ikyon.

In: Organic Chemistry Frontiers, Vol. 6, No. 5, 07.03.2019, p. 669-673.

Research output: Contribution to journalArticle

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