One-pot, three-component approach to diarylacetonitriles

Dileep Kumar Singh, Sure Siva Prasad, Jinhwang Kim, Ikyon Kim

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3 Citations (Scopus)

Abstract

Described herein is a novel one-pot, three-component reaction where aldehydes, electron-rich arenes, and TMSCN in the presence of BF 3 -OEt 2 allowed direct access to a number of diarylacetonitriles under mild reaction conditions in good to excellent yields. Implementation of this assembly protocol to a concise synthetic approach to shoreaphenol, a bioactive oligostilbenoid natural product, is also demonstrated.

Original languageEnglish
Pages (from-to)669-673
Number of pages5
JournalOrganic Chemistry Frontiers
Volume6
Issue number5
DOIs
Publication statusPublished - 2019 Mar 7

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All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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