Open-Bandgap Graphene-Based Field-Effect Transistor Using Oligo(phenylene-ethynylene) Interfacial Chemistry

Kyung Ho Kim, Sung Eun Seo, Chul Soon Park, Soomin Kim, Soohyun Lee, Choong Min Ryu, Dongeun Yong, Yoo Min Park, Oh Seok Kwon

Research output: Contribution to journalArticlepeer-review

Abstract

Organic interfacial compounds (OICs) are required as linkers for the highly stable and efficient immobilization of bioprobes in nanobiosensors using 2D nanomaterials such as graphene. Herein, we first demonstrated the fabrication of a field-effect transistor (FET) via a microelectromechanical system process after covalent functionalization on large-scale graphene by introducing oligo(phenylene-ethynylene)amine (OPE). OPE was compared to various OICs by density functional theory simulations and was confirmed to have a higher binding energy with graphene and a lower band gap than other OICs. OPE can improve the immobilization efficiency of a bioprobe by forming a self-assembly monolayer via anion-based reaction. Using this technology, Magainin I-conjugated OGMFET (MOGMFET) showed a high sensitivity, high selectivity, with a limit of detection of 100 cfu mL−1. These results indicate that the OPE OIC can be applied for stable and comfortable interfacing technology for biosensor fabrication.

Original languageEnglish
Article numbere202209726
JournalAngewandte Chemie - International Edition
Volume61
Issue number41
DOIs
Publication statusPublished - 2022 Oct 10

Bibliographical note

Funding Information:
This work was supported by Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry (IPET) and Korea Smart Farm R&D Foundation (KosFarm) through Smart Farm Innovation Technology Development Program, funded by Ministry of Agriculture, Food and Rural Affairs (MAFRA) and Ministry of Science and ICT (MSIT), Rural Development Administration (RDA) (421020‐03); the National Research Council of Science & Technology (NST) grant by the Korea government (MSIT) (No. CAP22011‐000); Korea Ministry of Environment (MOE) through Technology Development Project for Safety Management of Household Chemical Products Program, funded by Korea Ministry of Environment (MOE) (2022002980005, 1485018893); National R&D Program of National Research Foundation of Korea (NRF) funded by Ministry of Science and ICT (NRF‐2021M3H4A4079381); Nanomedical Devices Development Project of NNFC; the Korea Research Institute of Bioscience and Biotechnology (KRIBB) Research Initiative Program (KGM2112234).

Publisher Copyright:
© 2022 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Fingerprint

Dive into the research topics of 'Open-Bandgap Graphene-Based Field-Effect Transistor Using Oligo(phenylene-ethynylene) Interfacial Chemistry'. Together they form a unique fingerprint.

Cite this