Optical coherence tomography-based evaluation of malapposed strut coverage after drug-eluting stent implantation

Byeong Keuk Kim, Dong Ho Shin, Jung Sun Kim, Young Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong Ki Hong

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Minimal data exist regarding the use of optical coherence tomography (OCT) to evaluate malapposed strut coverage following implantation of drug-eluting stents (DESs). Follow-up OCT examination after DES implantation was performed in 368 patients with 406 lesions at our institute. We assessed the status of malapposed strut coverage that was identified via OCT in 92 (23 %) lesions. An absence of uncovered struts among malapposed struts was defined as completely covered (CC) malapposition; the presence of uncovered struts was defined as incompletely covered (IC) malapposition. Among the 92 lesions with malapposed DES struts, CC malapposition was detected in 47 lesions (51 %). Compared to lesions with IC malapposition (n = 45, 49 %), lesions with CC malapposition showed a significantly lower percentage of uncovered struts among all the struts (14.9 ± 14.5 vs. 4.4 ± 8.5 %, respectively, p\0.001) and among the other wellapposed struts without malapposition (12.7 ± 12.8 vs. 4.5 ± 8.7 %, respectively, p = 0.001). The degree of malapposed strut coverage was significantly different according to the type of DES; new-generation DESs such as everolimus- or zotarolimus-eluting stents showed a higher incidence of CC malapposition, compared to first-generation DESs such as sirolimusor paclitaxel-eluting stents (82 vs. 34 %, respectively, p\0.001). This study showed the complete coverage in about 50 % of the lesions with malapposed DES struts on follow-up OCT. The degree of malapposed DES strut coverage was strongly affected by the type of implanted DESs.

Original languageEnglish
Pages (from-to)1887-1894
Number of pages8
JournalInternational Journal of Cardiovascular Imaging
Volume28
Issue number8
DOIs
Publication statusPublished - 2012 Dec 1

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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