Optimal conditions for the removal of house dust mite, dog dander, and pollen allergens using mechanical laundry

Soo Young Choi, In Yong Lee, Jung Ho Sohn, Yong Won Lee, Yoo Seob Shin, Tae Soon Yong, Chein Soo Hong, Jung Won Park

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Background: Mechanical laundry is an effective tool for the environmental control of allergens, but the optimal conditions for removing allergens are not yet clear. Objective: To evaluate the optimal conditions of mechanical laundry for the removal of house dust mite (HDM), dog dander, and pollen allergens. Methods: The 4 washing modes of 30°C (86°F), 40°C (104°F), 60°C (140°F), and steam water (SW) with detergent were evaluated. Allergen removal performance was assayed using a 2-site enzyme-linked immunosorbent assay (ELISA) or an ELISA inhibition test. Results: Using the 30°C and 40°C washing modes, only 6.5% and 9.6% of Dermatophagoides farinae, respectively, were killed. However, using the 60°C and SW washing modes, all HDMs were killed. The amounts of Der f 1 remaining after the 30°C, 40°C, 60°C, and SW washing modes were 26.8%, 2.4%, 1.3%, and 0.6%, respectively, with unmanipulated contaminated sheets. The effects of rinse on Der f 1 levels after the 30°C washing were greater compared with those after the 40°C, 60°C, and SW modes. The amounts of Can f 1 in the extractions after washing were 0.3% to 1.3% for all modes, and all extracts, even without a rinse, did not inhibit specific IgE binding to dog allergens according to ELISA. The remaining pollen allergen levels after washing were lower in the 60°C and SW modes than in the lower temperature modes. However, the levels did not differ among the various washing modes after rinsing once. Conclusion: Water temperature and number of rinses are critical factors for the removal of HDM, dog dander, and pollen allergens.

Original languageEnglish
Pages (from-to)583-588
Number of pages6
JournalAnnals of Allergy, Asthma and Immunology
Issue number6
Publication statusPublished - 2008 Jun

Bibliographical note

Funding Information:
Funding Sources: This work was supported by a grant from LG Electronics and by Clinical Research Center for Chronic Obstructive Airway Disease grant 0412-CR03-0704-0001 from the Korean Ministry of Health and Welfare .

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine


Dive into the research topics of 'Optimal conditions for the removal of house dust mite, dog dander, and pollen allergens using mechanical laundry'. Together they form a unique fingerprint.

Cite this