Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla

Seung Hyun Kim, Ho Kyung Kim, Eun Sun Yang, Ki Yong Lee, Sang Du Kim, Young Choong Kim, Sang Hyun Sung

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Method development based on pressurized liquid extraction technique was investigated for the extraction of spicatoside A from Liriope platyphylla. Determination of spicatoside A was carried out by high performance liquid chromatography coupled with charged aerosol detector. Central composite design consisting of 15 experimental points in triplicate was applied to evaluated the effects of three independent variables, namely extraction time (min), extraction temperature (°C) and ethanol concentration (%) on the acquired content of spicatoside A. Response surface analysis indicated that the highest predicted content of spicatoside A might be 0.0161% of the optimized extract at extraction time 20 min, extraction temperature 130 °C and ethanol concentration 86%. Under this optimal condition, the experimental value was 0.0157%, which agrees with the predicted one by analysis of variance.

Original languageEnglish
Pages (from-to)168-172
Number of pages5
JournalSeparation and Purification Technology
Volume71
Issue number2
DOIs
Publication statusPublished - 2010 Feb 18

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Liquids
Ethanol
Surface analysis
High performance liquid chromatography
Analysis of variance (ANOVA)
Aerosols
5-(1-(glucopyranosyloxymethyl)ethenyl)-2-methyl-2-cyclohexen-1-one
Detectors
Temperature
Composite materials

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Filtration and Separation

Cite this

Kim, Seung Hyun ; Kim, Ho Kyung ; Yang, Eun Sun ; Lee, Ki Yong ; Kim, Sang Du ; Kim, Young Choong ; Sung, Sang Hyun. / Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla. In: Separation and Purification Technology. 2010 ; Vol. 71, No. 2. pp. 168-172.
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abstract = "Method development based on pressurized liquid extraction technique was investigated for the extraction of spicatoside A from Liriope platyphylla. Determination of spicatoside A was carried out by high performance liquid chromatography coupled with charged aerosol detector. Central composite design consisting of 15 experimental points in triplicate was applied to evaluated the effects of three independent variables, namely extraction time (min), extraction temperature (°C) and ethanol concentration ({\%}) on the acquired content of spicatoside A. Response surface analysis indicated that the highest predicted content of spicatoside A might be 0.0161{\%} of the optimized extract at extraction time 20 min, extraction temperature 130 °C and ethanol concentration 86{\%}. Under this optimal condition, the experimental value was 0.0157{\%}, which agrees with the predicted one by analysis of variance.",
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Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla. / Kim, Seung Hyun; Kim, Ho Kyung; Yang, Eun Sun; Lee, Ki Yong; Kim, Sang Du; Kim, Young Choong; Sung, Sang Hyun.

In: Separation and Purification Technology, Vol. 71, No. 2, 18.02.2010, p. 168-172.

Research output: Contribution to journalArticle

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AU - Kim, Seung Hyun

AU - Kim, Ho Kyung

AU - Yang, Eun Sun

AU - Lee, Ki Yong

AU - Kim, Sang Du

AU - Kim, Young Choong

AU - Sung, Sang Hyun

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