Optimization of synthesizing leucine-binding nano-sized magnetite by a two-step transformation

Dong Geun Lee, Youn-Sang Bae, Shao Long Tie, Mir Kim, Ik Sung Ahn, Chang-Ha Lee

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The optimum conditions for synthesizing leucine (Leu)-binding nano-sized magnetite (NSM) particles by a two-step transformation (TST) process were studied. The formation and magnetization of as-synthesized NSM particles were investigated through variation of the acidity, the type of surface modifier, and the nature of the acid for pH adjustment. With increased acidity, the saturation magnetization of the NSM particles decreased, but the amount of Leu coated on the surface of NSM particles increased. After the influence of hydroxyl (OH-) groups on the surface of NSM particles was removed by using the dicarboxyl anion (C2O 4 2- ) as a ligand in the first step, Leu was successfully bound with NSM particles in the second step. However, when polyethylene glycol (PEG) was used as a surface modifier, it was difficult to form the Leu-to-NSM particle complex. In terms of the acid used to modify pH, H2SO4 was slightly less effective than HCl in achieving saturation magnetization because the coordination for SO 4 2- anions is stronger than that of Cl- anions. The preparation of other amino acid-binding NSM particles can be optimized in an analogous manner.

Original languageEnglish
Pages (from-to)144-148
Number of pages5
JournalKorean Journal of Chemical Engineering
Volume25
Issue number1
DOIs
Publication statusPublished - 2008 Jan 1

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Ferrosoferric Oxide
Magnetite
Leucine
Anions
Negative ions
Saturation magnetization
Acidity
Acids
Hydroxyl Radical
Polyethylene glycols
Amino acids
Magnetization
Ligands
Amino Acids

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

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abstract = "The optimum conditions for synthesizing leucine (Leu)-binding nano-sized magnetite (NSM) particles by a two-step transformation (TST) process were studied. The formation and magnetization of as-synthesized NSM particles were investigated through variation of the acidity, the type of surface modifier, and the nature of the acid for pH adjustment. With increased acidity, the saturation magnetization of the NSM particles decreased, but the amount of Leu coated on the surface of NSM particles increased. After the influence of hydroxyl (OH-) groups on the surface of NSM particles was removed by using the dicarboxyl anion (C2O 4 2- ) as a ligand in the first step, Leu was successfully bound with NSM particles in the second step. However, when polyethylene glycol (PEG) was used as a surface modifier, it was difficult to form the Leu-to-NSM particle complex. In terms of the acid used to modify pH, H2SO4 was slightly less effective than HCl in achieving saturation magnetization because the coordination for SO 4 2- anions is stronger than that of Cl- anions. The preparation of other amino acid-binding NSM particles can be optimized in an analogous manner.",
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Optimization of synthesizing leucine-binding nano-sized magnetite by a two-step transformation. / Lee, Dong Geun; Bae, Youn-Sang; Tie, Shao Long; Kim, Mir; Ahn, Ik Sung; Lee, Chang-Ha.

In: Korean Journal of Chemical Engineering, Vol. 25, No. 1, 01.01.2008, p. 144-148.

Research output: Contribution to journalArticle

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