Optimized conditions for the extraction of eupatilin in Artemisia asiatica by pressurized liquid extraction

Seung Hyun Kim, Jin Ho Park, Bo Ram Kim, Eun Ju Kim, Hyo Jin Kim, Yekyung Cho, Ki Yong Lee, Sang Hyun Sung

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The effect of temperature and solvent on the extraction of Artemisia asiatica using pressurized liquid extraction was examined. These two parameters were operated according to central composite design followed by response surface analysis to obtain the highest extraction efficiency. Determination of eupatilin was carried out by high performance liquid chromatography coupled with a diode array detector. While the rise in temperature could increase the yield of the total extract, the content of eupatilin was decreased in high temperature. In addition, high ethanol proportion maximized the contents of eupatilin in the total extract.

Original languageEnglish
Pages (from-to)1772-1783
Number of pages12
JournalSeparation Science and Technology
Volume44
Issue number8
DOIs
Publication statusPublished - 2009 Jun 1

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)
  • Process Chemistry and Technology
  • Filtration and Separation

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