Optimized conditions for the extraction of eupatilin in Artemisia asiatica by pressurized liquid extraction

Seung Hyun Kim; Jin Ho Park; Bo Ram Kim; Eun Ju Kim; Hyo Jin Kim; Yekyung Cho; Ki Yong Lee; Sang Hyun Sung

doi:10.1080/01496390902775794

Optimized conditions for the extraction of eupatilin in Artemisia asiatica by pressurized liquid extraction

Seung Hyun Kim, Jin Ho Park, Bo Ram Kim, Eun Ju Kim, Hyo Jin Kim, Yekyung Cho, Ki Yong Lee, Sang Hyun Sung

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The effect of temperature and solvent on the extraction of Artemisia asiatica using pressurized liquid extraction was examined. These two parameters were operated according to central composite design followed by response surface analysis to obtain the highest extraction efficiency. Determination of eupatilin was carried out by high performance liquid chromatography coupled with a diode array detector. While the rise in temperature could increase the yield of the total extract, the content of eupatilin was decreased in high temperature. In addition, high ethanol proportion maximized the contents of eupatilin in the total extract.

Original language	English
Pages (from-to)	1772-1783
Number of pages	12
Journal	Separation Science and Technology
Volume	44
Issue number	8
DOIs	https://doi.org/10.1080/01496390902775794
Publication status	Published - 2009 Jun

Bibliographical note

Funding Information:
This research was supported by a grant PF06200-00 from Plant Diversity Research Center of the 21st Century Frontier Research Program funded by the Ministry of Science and Technology, Korea.

All Science Journal Classification (ASJC) codes

Chemistry(all)
Chemical Engineering(all)
Process Chemistry and Technology
Filtration and Separation

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10.1080/01496390902775794

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title = "Optimized conditions for the extraction of eupatilin in Artemisia asiatica by pressurized liquid extraction",

abstract = "The effect of temperature and solvent on the extraction of Artemisia asiatica using pressurized liquid extraction was examined. These two parameters were operated according to central composite design followed by response surface analysis to obtain the highest extraction efficiency. Determination of eupatilin was carried out by high performance liquid chromatography coupled with a diode array detector. While the rise in temperature could increase the yield of the total extract, the content of eupatilin was decreased in high temperature. In addition, high ethanol proportion maximized the contents of eupatilin in the total extract.",

author = "Kim, {Seung Hyun} and Park, {Jin Ho} and Kim, {Bo Ram} and Kim, {Eun Ju} and Kim, {Hyo Jin} and Yekyung Cho and Lee, {Ki Yong} and Sung, {Sang Hyun}",

note = "Funding Information: This research was supported by a grant PF06200-00 from Plant Diversity Research Center of the 21st Century Frontier Research Program funded by the Ministry of Science and Technology, Korea.",

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AU - Kim, Seung Hyun

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AU - Kim, Eun Ju

AU - Kim, Hyo Jin

AU - Cho, Yekyung

AU - Lee, Ki Yong

AU - Sung, Sang Hyun

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PY - 2009/6

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Optimized conditions for the extraction of eupatilin in Artemisia asiatica by pressurized liquid extraction

Abstract

Bibliographical note

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