Abstract
The effect of temperature and solvent on the extraction of Artemisia asiatica using pressurized liquid extraction was examined. These two parameters were operated according to central composite design followed by response surface analysis to obtain the highest extraction efficiency. Determination of eupatilin was carried out by high performance liquid chromatography coupled with a diode array detector. While the rise in temperature could increase the yield of the total extract, the content of eupatilin was decreased in high temperature. In addition, high ethanol proportion maximized the contents of eupatilin in the total extract.
| Original language | English |
|---|---|
| Pages (from-to) | 1772-1783 |
| Number of pages | 12 |
| Journal | Separation Science and Technology |
| Volume | 44 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2009 Jun 1 |
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All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Chemical Engineering(all)
- Process Chemistry and Technology
- Filtration and Separation
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Optimized conditions for the extraction of eupatilin in Artemisia asiatica by pressurized liquid extraction. / Kim, Seung Hyun; Park, Jin Ho; Kim, Bo Ram; Kim, Eun Ju; Kim, Hyo Jin; Cho, Yekyung; Lee, Ki Yong; Sung, Sang Hyun.
In: Separation Science and Technology, Vol. 44, No. 8, 01.06.2009, p. 1772-1783.Research output: Contribution to journal › Article
TY - JOUR
T1 - Optimized conditions for the extraction of eupatilin in Artemisia asiatica by pressurized liquid extraction
AU - Kim, Seung Hyun
AU - Park, Jin Ho
AU - Kim, Bo Ram
AU - Kim, Eun Ju
AU - Kim, Hyo Jin
AU - Cho, Yekyung
AU - Lee, Ki Yong
AU - Sung, Sang Hyun
PY - 2009/6/1
Y1 - 2009/6/1
N2 - The effect of temperature and solvent on the extraction of Artemisia asiatica using pressurized liquid extraction was examined. These two parameters were operated according to central composite design followed by response surface analysis to obtain the highest extraction efficiency. Determination of eupatilin was carried out by high performance liquid chromatography coupled with a diode array detector. While the rise in temperature could increase the yield of the total extract, the content of eupatilin was decreased in high temperature. In addition, high ethanol proportion maximized the contents of eupatilin in the total extract.
AB - The effect of temperature and solvent on the extraction of Artemisia asiatica using pressurized liquid extraction was examined. These two parameters were operated according to central composite design followed by response surface analysis to obtain the highest extraction efficiency. Determination of eupatilin was carried out by high performance liquid chromatography coupled with a diode array detector. While the rise in temperature could increase the yield of the total extract, the content of eupatilin was decreased in high temperature. In addition, high ethanol proportion maximized the contents of eupatilin in the total extract.
UR - http://www.scopus.com/inward/record.url?scp=70449515108&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70449515108&partnerID=8YFLogxK
U2 - 10.1080/01496390902775794
DO - 10.1080/01496390902775794
M3 - Article
AN - SCOPUS:70449515108
VL - 44
SP - 1772
EP - 1783
JO - Separation Science and Technology
JF - Separation Science and Technology
SN - 0149-6395
IS - 8
ER -