Oral Papillomatosis in Immunocompromised Patients: A Case Series of Kidney Transplant Recipients and Myelodysplastic Syndrome

Eun Jung Kwak, Yun Hee Choi, Wonse Park, Eunae Sandra Cho

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Solitary papilloma is a human papillomavirus (HPV)-induced benign indolent epithelial tumor with limited growth, whereas papillomatosis is an entirely different entity. Papillomatosis requires attention because of its aggressive and recurrent clinical progress with risks of dysplastic and malignant transformation. Recurrent respiratory papillomatosis (RRP) has a high prevalence of dysplasia and reports of transformation to carcinoma-ex-papillomatosis, especially when associated with low-risk HPV type 11. Although papillomatosis seldom occurs in the oral cavity, this report describes 3 cases of oral papillomatosis in immunocompromised patients, with 1 case identified as having HPV type 11. Two cases were kidney transplant recipients and the other case had a history of myelodysplastic syndrome followed by allogeneic bone marrow transplantation and graft-versus-host disease. Oral papillomatosis might be problematic, as in RRP, and periodic oral examination for persistent recurrences and malignant transformation can be beneficial to immunocompromised patients.

Original languageEnglish
Pages (from-to)128-133
Number of pages6
JournalJournal of Oral and Maxillofacial Surgery
Volume76
Issue number1
DOIs
Publication statusPublished - 2018 Jan

Bibliographical note

Publisher Copyright:
© 2017 American Association of Oral and Maxillofacial Surgeons

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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