Abstract
(Chemical Equation Presented) The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh 3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.
Original language | English |
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Pages (from-to) | 4687-4690 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 6 |
Issue number | 25 |
DOIs | |
Publication status | Published - 2004 Dec 9 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry