Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst

Sung Gon Lim, Jeong Ae Ahn, Chul-Ho Jun

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

(Chemical Equation Presented) The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh 3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.

Original languageEnglish
Pages (from-to)4687-4690
Number of pages4
JournalOrganic Letters
Volume6
Issue number25
DOIs
Publication statusPublished - 2004 Dec 9

Fingerprint

alkylation
Alkylation
Alkenes
Ketones
ketones
alkenes
catalysts
Catalysts
Imines
Functional groups
imines
hydrolysis
Hydrolysis
ketimine

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Lim, Sung Gon ; Ahn, Jeong Ae ; Jun, Chul-Ho. / Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst. In: Organic Letters. 2004 ; Vol. 6, No. 25. pp. 4687-4690.
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Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst. / Lim, Sung Gon; Ahn, Jeong Ae; Jun, Chul-Ho.

In: Organic Letters, Vol. 6, No. 25, 09.12.2004, p. 4687-4690.

Research output: Contribution to journalArticle

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