Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst

Sung Gon Lim, Jeong Ae Ahn, Chui Ho Jun

Research output: Contribution to journalArticle

102 Citations (Scopus)

Abstract

(Chemical Equation Presented) The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh 3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.

Original languageEnglish
Pages (from-to)4687-4690
Number of pages4
JournalOrganic Letters
Volume6
Issue number25
DOIs
Publication statusPublished - 2004 Dec 9

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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