Abstract
(Chemical Equation Presented) The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh 3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.
| Original language | English |
|---|---|
| Pages (from-to) | 4687-4690 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 6 |
| Issue number | 25 |
| DOIs | |
| Publication status | Published - 2004 Dec 9 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Fingerprint Dive into the research topics of 'Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst'. Together they form a unique fingerprint.
Cite this
Lim, S. G., Ahn, J. A., & Jun, C. H. (2004). Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst. Organic Letters, 6(25), 4687-4690. https://doi.org/10.1021/ol048095n