Abstract
(Chemical Equation Presented) The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh 3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.
| Original language | English |
|---|---|
| Pages (from-to) | 4687-4690 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 6 |
| Issue number | 25 |
| DOIs | |
| Publication status | Published - 2004 Dec 9 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
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Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst. / Lim, Sung Gon; Ahn, Jeong Ae; Jun, Chui Ho.
In: Organic Letters, Vol. 6, No. 25, 09.12.2004, p. 4687-4690.Research output: Contribution to journal › Article
TY - JOUR
T1 - Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(I) catalyst
AU - Lim, Sung Gon
AU - Ahn, Jeong Ae
AU - Jun, Chui Ho
PY - 2004/12/9
Y1 - 2004/12/9
N2 - (Chemical Equation Presented) The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh 3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.
AB - (Chemical Equation Presented) The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh 3)3RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.
UR - http://www.scopus.com/inward/record.url?scp=11444263216&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=11444263216&partnerID=8YFLogxK
U2 - 10.1021/ol048095n
DO - 10.1021/ol048095n
M3 - Article
C2 - 15575661
AN - SCOPUS:11444263216
VL - 6
SP - 4687
EP - 4690
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 25
ER -