Osmotic actuation for microfluidic components in point-of-care applications

Yu Chih Chen, Patrick Ingram, Xia Lou, Euisik Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

We present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics.

Original languageEnglish
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages1125-1128
Number of pages4
DOIs
Publication statusPublished - 2013 Apr 2
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: 2013 Jan 202013 Jan 24

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period13/1/2013/1/24

Fingerprint

actuation
Microfluidics
Pumps
Fluidics
Digital to analog conversion
pumps
digital to analog converters
control equipment
Resonators
fluidics
Diodes
Switches
Flow rate
switches
flow velocity
resonators
diodes
chips
Costs

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Chen, Y. C., Ingram, P., Lou, X., & Yoon, E. (2013). Osmotic actuation for microfluidic components in point-of-care applications. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 (pp. 1125-1128). [6474448] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474448
Chen, Yu Chih ; Ingram, Patrick ; Lou, Xia ; Yoon, Euisik. / Osmotic actuation for microfluidic components in point-of-care applications. IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. pp. 1125-1128 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).
@inproceedings{7cf600bbdb054376a1d7ac8bb83a4855,
title = "Osmotic actuation for microfluidic components in point-of-care applications",
abstract = "We present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics.",
author = "Chen, {Yu Chih} and Patrick Ingram and Xia Lou and Euisik Yoon",
year = "2013",
month = "4",
day = "2",
doi = "10.1109/MEMSYS.2013.6474448",
language = "English",
isbn = "9781467356558",
series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",
pages = "1125--1128",
booktitle = "IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013",

}

Chen, YC, Ingram, P, Lou, X & Yoon, E 2013, Osmotic actuation for microfluidic components in point-of-care applications. in IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013., 6474448, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 1125-1128, IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013, Taipei, Taiwan, Province of China, 13/1/20. https://doi.org/10.1109/MEMSYS.2013.6474448

Osmotic actuation for microfluidic components in point-of-care applications. / Chen, Yu Chih; Ingram, Patrick; Lou, Xia; Yoon, Euisik.

IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 1125-1128 6474448 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Osmotic actuation for microfluidic components in point-of-care applications

AU - Chen, Yu Chih

AU - Ingram, Patrick

AU - Lou, Xia

AU - Yoon, Euisik

PY - 2013/4/2

Y1 - 2013/4/2

N2 - We present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics.

AB - We present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics.

UR - http://www.scopus.com/inward/record.url?scp=84875459374&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875459374&partnerID=8YFLogxK

U2 - 10.1109/MEMSYS.2013.6474448

DO - 10.1109/MEMSYS.2013.6474448

M3 - Conference contribution

AN - SCOPUS:84875459374

SN - 9781467356558

T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

SP - 1125

EP - 1128

BT - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013

ER -

Chen YC, Ingram P, Lou X, Yoon E. Osmotic actuation for microfluidic components in point-of-care applications. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 1125-1128. 6474448. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474448