Osteonecrosis of the jaw related to everolimus: A case report

Dong Wook Kim, Young Soo Jung, Hyung Sik Park, Hwi Dong Jung

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Antiresorptive agent-related osteonecrosis of the jaw results in appreciable morbidity in affected patients. Nowadays many physicians prescribe an antiangiogenic agent for the management of malignant metastases. Everolimus is a serine-threonine kinase that acts as an inhibitor of mammalian target of rapamycin, which results in reduced growth of cells, angiogenesis, and survival of cells. We report the first case to our knowledge of osteonecrosis of the jaw that seemed to result from the additive effect of everolimus.

Original languageEnglish
Pages (from-to)e302-e304
JournalBritish Journal of Oral and Maxillofacial Surgery
Volume51
Issue number8
DOIs
Publication statusPublished - 2013 Dec

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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