Outcomes of hemodialysis in children: A 35-year experience at severance hospital

Hyun Seung Shin, Ji Young Oh, Se Jin Park, Ji Hong Kim, Jae Seung Lee, Jae Il Shin

Research output: Contribution to journalArticle

Abstract

Purpose: The aim of this study was to analyze the results of children treated with hemodialysis (HD) at Severance Hospital over 35 years in terms of incidence, etiologies, characteristics, complications, and clinical outcomes. Materials and Methods: We analyzed 46 children admitted to Severance Hospital who had undergone HD between January 1979 and December 2013. Results: The main etiologies of the 23 end-stage renal disease (ESRD) patients who had received HD were chronic glomerulonephritis (7 patients, 30.4%) and congenital anomalies of the kidney and urinary tract (7 patients, 30.4%), whereas the etiology of the 23 acute kidney injury (AKI) patients was hemolytic uremic syndrome (6 patients, 26.1%). Compared with ESRD patients, hemocatheter placement in the femoral vein was preferred over the subclavian or internal jugular vein in the AKI patients (p=0.012). The most common complication was catheter related complication (10 patients, 21.7%). The site of hemocatheter insertion was not related to the frequency of oozing. Placing the hemocatheter in the femoral vein resulted in significantly more events of catheter obstruction than insertion in the internal jugular vein or the subclavian vein (p=0.001). Disequilibrium syndrome occurred more frequently in older patients (p=0.004), as well as patients with a greater body weight (p=0.008) and a higher systolic and diastolic blood pressure before HD (systolic: p=0.021; diastolic: p=0.040). Conclusion: Based on the 35 years of experience in our center, HD can be sufficiently and safely carried out even in children without significant complications.

Original languageEnglish
Pages (from-to)1007-1014
Number of pages8
JournalYonsei medical journal
Volume56
Issue number4
DOIs
Publication statusPublished - 2015 Jul 1

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Renal Dialysis
Femoral Vein
Jugular Veins
Acute Kidney Injury
Chronic Kidney Failure
Catheter Obstruction
Blood Pressure
Subclavian Vein
Hemolytic-Uremic Syndrome
Glomerulonephritis
Catheters
Body Weight
Incidence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Shin, Hyun Seung ; Oh, Ji Young ; Park, Se Jin ; Kim, Ji Hong ; Lee, Jae Seung ; Shin, Jae Il. / Outcomes of hemodialysis in children : A 35-year experience at severance hospital. In: Yonsei medical journal. 2015 ; Vol. 56, No. 4. pp. 1007-1014.
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abstract = "Purpose: The aim of this study was to analyze the results of children treated with hemodialysis (HD) at Severance Hospital over 35 years in terms of incidence, etiologies, characteristics, complications, and clinical outcomes. Materials and Methods: We analyzed 46 children admitted to Severance Hospital who had undergone HD between January 1979 and December 2013. Results: The main etiologies of the 23 end-stage renal disease (ESRD) patients who had received HD were chronic glomerulonephritis (7 patients, 30.4{\%}) and congenital anomalies of the kidney and urinary tract (7 patients, 30.4{\%}), whereas the etiology of the 23 acute kidney injury (AKI) patients was hemolytic uremic syndrome (6 patients, 26.1{\%}). Compared with ESRD patients, hemocatheter placement in the femoral vein was preferred over the subclavian or internal jugular vein in the AKI patients (p=0.012). The most common complication was catheter related complication (10 patients, 21.7{\%}). The site of hemocatheter insertion was not related to the frequency of oozing. Placing the hemocatheter in the femoral vein resulted in significantly more events of catheter obstruction than insertion in the internal jugular vein or the subclavian vein (p=0.001). Disequilibrium syndrome occurred more frequently in older patients (p=0.004), as well as patients with a greater body weight (p=0.008) and a higher systolic and diastolic blood pressure before HD (systolic: p=0.021; diastolic: p=0.040). Conclusion: Based on the 35 years of experience in our center, HD can be sufficiently and safely carried out even in children without significant complications.",
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Outcomes of hemodialysis in children : A 35-year experience at severance hospital. / Shin, Hyun Seung; Oh, Ji Young; Park, Se Jin; Kim, Ji Hong; Lee, Jae Seung; Shin, Jae Il.

In: Yonsei medical journal, Vol. 56, No. 4, 01.07.2015, p. 1007-1014.

Research output: Contribution to journalArticle

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