Overlooked management and risk factors for anemia in patients with intestinal Behçet's disease in actual clinical practice

Bun Kim, Soo Jung Park, Sung Pil Hong, JaeHee Cheon, Tae Il Kim, Won Ho Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background/Aims: Anemia in patients with inflammatory bowel disease significantly affects the quality of life. The aim of this study was to investigate the frequency of and risk factors for anemia and to describe the management of anemia in patients with intestinal Behçet's disease (BD) in actual clinical practice. Methods: We included 64 patients with intestinal BD who visited the outpatient clinic of a tertiary referral center in June 2011 and had available laboratory data for the subsequent 6 months. Results: Anemia was detected in 26 patients (40.6%). After 6 months, anemia was still present in 14 of these patients (53.8%). The cause of anemia was investigated in eight patients (30.8%), and oral iron supplementation was prescribed to four patients (15.4%). Of these four patients, two (50%) recovered completely within 6 months. Anemia was associated with a high Disease Activity Index for Intestinal Behçet's Disease (DAIBD, p=0.024), erythrocyte sedimentation rate (p=0.003), and C-reactive protein (p=0.049) in univariate analysis. In multivariate analysis, the factor predictive for anemia in patients with intestinal BD was a higher DAIBD (≥40; odds ratio, 4.08; 95% confidence interval, 1.21 to 13.71; p=0.023). Conclusions: Although anemia is common in intestinal BD patients, its clinical importance is overlooked in daily practice. Moderate to severe disease activity is predictive of anemia.

Original languageEnglish
Pages (from-to)750-755
Number of pages6
JournalGut and Liver
Volume9
Issue number6
DOIs
Publication statusPublished - 2015 Nov 1

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Intestinal Diseases
Anemia
Blood Sedimentation
Ambulatory Care Facilities
Inflammatory Bowel Diseases
Tertiary Care Centers
C-Reactive Protein
Multivariate Analysis
Iron
Odds Ratio
Quality of Life
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Kim, Bun ; Park, Soo Jung ; Hong, Sung Pil ; Cheon, JaeHee ; Kim, Tae Il ; Kim, Won Ho. / Overlooked management and risk factors for anemia in patients with intestinal Behçet's disease in actual clinical practice. In: Gut and Liver. 2015 ; Vol. 9, No. 6. pp. 750-755.
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abstract = "Background/Aims: Anemia in patients with inflammatory bowel disease significantly affects the quality of life. The aim of this study was to investigate the frequency of and risk factors for anemia and to describe the management of anemia in patients with intestinal Beh{\cc}et's disease (BD) in actual clinical practice. Methods: We included 64 patients with intestinal BD who visited the outpatient clinic of a tertiary referral center in June 2011 and had available laboratory data for the subsequent 6 months. Results: Anemia was detected in 26 patients (40.6{\%}). After 6 months, anemia was still present in 14 of these patients (53.8{\%}). The cause of anemia was investigated in eight patients (30.8{\%}), and oral iron supplementation was prescribed to four patients (15.4{\%}). Of these four patients, two (50{\%}) recovered completely within 6 months. Anemia was associated with a high Disease Activity Index for Intestinal Beh{\cc}et's Disease (DAIBD, p=0.024), erythrocyte sedimentation rate (p=0.003), and C-reactive protein (p=0.049) in univariate analysis. In multivariate analysis, the factor predictive for anemia in patients with intestinal BD was a higher DAIBD (≥40; odds ratio, 4.08; 95{\%} confidence interval, 1.21 to 13.71; p=0.023). Conclusions: Although anemia is common in intestinal BD patients, its clinical importance is overlooked in daily practice. Moderate to severe disease activity is predictive of anemia.",
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Overlooked management and risk factors for anemia in patients with intestinal Behçet's disease in actual clinical practice. / Kim, Bun; Park, Soo Jung; Hong, Sung Pil; Cheon, JaeHee; Kim, Tae Il; Kim, Won Ho.

In: Gut and Liver, Vol. 9, No. 6, 01.11.2015, p. 750-755.

Research output: Contribution to journalArticle

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