Palladium-catalyzed α-arylation of aryloxyketones for the synthesis of 2,3-Disubstituted benzofurans

Jin Ho Lee, Myungock Kim, Ikyon Kim

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

A highly efficient palladium-catalyzed α-arylation of aryloxyketones has been developed, allowing for facile installation of various (hetero)aryl groups at C2 position in good to excellent yields. Subsequent cyclodehydration of the resulting α-arylated aryloxyketones provided rapid access to diverse 2,3-disubstitured benzofurans.

Original languageEnglish
Pages (from-to)6153-6163
Number of pages11
JournalJournal of Organic Chemistry
Volume79
Issue number13
DOIs
Publication statusPublished - 2014 Jul 3

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Palladium
benzofuran

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

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Palladium-catalyzed α-arylation of aryloxyketones for the synthesis of 2,3-Disubstituted benzofurans. / Lee, Jin Ho; Kim, Myungock; Kim, Ikyon.

In: Journal of Organic Chemistry, Vol. 79, No. 13, 03.07.2014, p. 6153-6163.

Research output: Contribution to journalArticle

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