Parkinsonism with basal ganglia lesions in a patient with uremia: Evidence of vasogenic edema

Phil Hyu Lee, Dong Hun Shin, Ji Won Kim, Young Soo Song, Heung Soo Kim

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39 Citations (Scopus)


Parkinsonian syndromes associated with basal ganglia pathology have very rarely been reported in patients with end-stage renal failure. The nature and pathophysiology of the basal ganglia lesion responsible for parkinsonism were unknown. A 48-year-old man who had advanced renal failure developed disturbance of balance and gait and decreased spontaneity. Brain magnetic resonance (MR) imaging disclosed bilateral basal ganglia lesions. By the finding of diffusion-weighted image, the apparent diffusion coefficient map, MR angiography, and SPECT, we suggest that the basal ganglia lesions may be the result of vasogenic edema attributable to focal hyperemia secondary to abnormal dilatation of small vessels.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalParkinsonism and Related Disorders
Issue number2
Publication statusPublished - 2006 Mar 1


All Science Journal Classification (ASJC) codes

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology

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