Pd/C-Catalyzed Carbonylative Esterification of Aryl Halides with Alcohols by Using Oxiranes as CO Sources

Byul Hana Min, Dong Su Kim, Hyo Soon Park, Chul Ho Jun

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10 Citations (Scopus)

Abstract

A carbonylative esterification reaction between aryl bromides and alcohols, promoted by Pd/C and NaF in the presence of oxiranes, has been developed. In this process, oxiranes serve as sources of carbon monoxide by their conversion to aldehydes through a palladium-promoted Meinwald rearrangement pathway. Intramolecular versions of this process serve as methods for the synthesis of lactones and phthalimides. CO gas free! A carbonylative esterification reaction between aryl bromides and alcohols, promoted by Pd/C and NaF in the presence of oxiranes, has been developed. In this process, oxiranes serve as sources of carbon monoxide by their conversion to aldehydes through a palladium-promoted Meinwald rearrangement pathway (see scheme).

Original languageEnglish
Pages (from-to)6234-6238
Number of pages5
JournalChemistry - A European Journal
Volume22
Issue number18
DOIs
Publication statusPublished - 2016 Apr 25

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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