Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex

Hee Kim Joo, Tae Lee Jong, Eunkyung Kim, Yong Won Jong, Myeong Jin Kim, Doo Lee Jong, Joon Hong Sung

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objective: To evaluate the usefulness of a beta-emitting radionuclide (holmium-166-chitosan complex) as a sclerosing agent for the treatment of renal cysts. Materials and Methods: Using 10-30 mCi of holmium-166-chitosan complex, 20 renal cysts in 17 patients (14 male and 3 female patients, ranging in age from 47 to 82 years) were treated by percutaneous sclerotherapy under ultrasonographic guidance. The volume of the cysts before and after the sclerotherapy and the percentage change in volume were calculated in order to evaluate the response to therapy, which was classified as either complete regression (invisible), nearly complete regression (< 15 volume% of initial volume), partial regression (15-50 volume%) or no regression (> 50 volume%). Results: The follow-up period ranged from 6 to 36 months (mean 28 months). Eighteen cysts (90%) regressed completely (n = 11, 55%) or near-completely (n = 7, 35%). Partial regression was obtained in one patient (5%) and there was no regression in one patient (5%). No significant complications were encountered. Conclusion: The holmium-166-chitosan complex seems to be useful as a new painless sclerosing agent for the treatment of renal cysts with no significant complications.

Original languageEnglish
Pages (from-to)128-133
Number of pages6
JournalKorean Journal of Radiology
Volume5
Issue number2
Publication statusPublished - 2004 Apr 1

Fingerprint

Sclerotherapy
Radioisotopes
Cysts
Kidney
Sclerosing Solutions
Therapeutics
(166)holmium-chitosan complex

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Joo, H. K., Jong, T. L., Kim, E., Jong, Y. W., Kim, M. J., Jong, D. L., & Sung, J. H. (2004). Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex. Korean Journal of Radiology, 5(2), 128-133.
Joo, Hee Kim ; Jong, Tae Lee ; Kim, Eunkyung ; Jong, Yong Won ; Kim, Myeong Jin ; Jong, Doo Lee ; Sung, Joon Hong. / Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex. In: Korean Journal of Radiology. 2004 ; Vol. 5, No. 2. pp. 128-133.
@article{ee53d79d69ca46f7bbbb45b04f809c90,
title = "Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex",
abstract = "Objective: To evaluate the usefulness of a beta-emitting radionuclide (holmium-166-chitosan complex) as a sclerosing agent for the treatment of renal cysts. Materials and Methods: Using 10-30 mCi of holmium-166-chitosan complex, 20 renal cysts in 17 patients (14 male and 3 female patients, ranging in age from 47 to 82 years) were treated by percutaneous sclerotherapy under ultrasonographic guidance. The volume of the cysts before and after the sclerotherapy and the percentage change in volume were calculated in order to evaluate the response to therapy, which was classified as either complete regression (invisible), nearly complete regression (< 15 volume{\%} of initial volume), partial regression (15-50 volume{\%}) or no regression (> 50 volume{\%}). Results: The follow-up period ranged from 6 to 36 months (mean 28 months). Eighteen cysts (90{\%}) regressed completely (n = 11, 55{\%}) or near-completely (n = 7, 35{\%}). Partial regression was obtained in one patient (5{\%}) and there was no regression in one patient (5{\%}). No significant complications were encountered. Conclusion: The holmium-166-chitosan complex seems to be useful as a new painless sclerosing agent for the treatment of renal cysts with no significant complications.",
author = "Joo, {Hee Kim} and Jong, {Tae Lee} and Eunkyung Kim and Jong, {Yong Won} and Kim, {Myeong Jin} and Jong, {Doo Lee} and Sung, {Joon Hong}",
year = "2004",
month = "4",
day = "1",
language = "English",
volume = "5",
pages = "128--133",
journal = "Korean Journal of Radiology",
issn = "1229-6929",
publisher = "Korean Radiological Society",
number = "2",

}

Joo, HK, Jong, TL, Kim, E, Jong, YW, Kim, MJ, Jong, DL & Sung, JH 2004, 'Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex', Korean Journal of Radiology, vol. 5, no. 2, pp. 128-133.

Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex. / Joo, Hee Kim; Jong, Tae Lee; Kim, Eunkyung; Jong, Yong Won; Kim, Myeong Jin; Jong, Doo Lee; Sung, Joon Hong.

In: Korean Journal of Radiology, Vol. 5, No. 2, 01.04.2004, p. 128-133.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex

AU - Joo, Hee Kim

AU - Jong, Tae Lee

AU - Kim, Eunkyung

AU - Jong, Yong Won

AU - Kim, Myeong Jin

AU - Jong, Doo Lee

AU - Sung, Joon Hong

PY - 2004/4/1

Y1 - 2004/4/1

N2 - Objective: To evaluate the usefulness of a beta-emitting radionuclide (holmium-166-chitosan complex) as a sclerosing agent for the treatment of renal cysts. Materials and Methods: Using 10-30 mCi of holmium-166-chitosan complex, 20 renal cysts in 17 patients (14 male and 3 female patients, ranging in age from 47 to 82 years) were treated by percutaneous sclerotherapy under ultrasonographic guidance. The volume of the cysts before and after the sclerotherapy and the percentage change in volume were calculated in order to evaluate the response to therapy, which was classified as either complete regression (invisible), nearly complete regression (< 15 volume% of initial volume), partial regression (15-50 volume%) or no regression (> 50 volume%). Results: The follow-up period ranged from 6 to 36 months (mean 28 months). Eighteen cysts (90%) regressed completely (n = 11, 55%) or near-completely (n = 7, 35%). Partial regression was obtained in one patient (5%) and there was no regression in one patient (5%). No significant complications were encountered. Conclusion: The holmium-166-chitosan complex seems to be useful as a new painless sclerosing agent for the treatment of renal cysts with no significant complications.

AB - Objective: To evaluate the usefulness of a beta-emitting radionuclide (holmium-166-chitosan complex) as a sclerosing agent for the treatment of renal cysts. Materials and Methods: Using 10-30 mCi of holmium-166-chitosan complex, 20 renal cysts in 17 patients (14 male and 3 female patients, ranging in age from 47 to 82 years) were treated by percutaneous sclerotherapy under ultrasonographic guidance. The volume of the cysts before and after the sclerotherapy and the percentage change in volume were calculated in order to evaluate the response to therapy, which was classified as either complete regression (invisible), nearly complete regression (< 15 volume% of initial volume), partial regression (15-50 volume%) or no regression (> 50 volume%). Results: The follow-up period ranged from 6 to 36 months (mean 28 months). Eighteen cysts (90%) regressed completely (n = 11, 55%) or near-completely (n = 7, 35%). Partial regression was obtained in one patient (5%) and there was no regression in one patient (5%). No significant complications were encountered. Conclusion: The holmium-166-chitosan complex seems to be useful as a new painless sclerosing agent for the treatment of renal cysts with no significant complications.

UR - http://www.scopus.com/inward/record.url?scp=3242681878&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3242681878&partnerID=8YFLogxK

M3 - Article

VL - 5

SP - 128

EP - 133

JO - Korean Journal of Radiology

JF - Korean Journal of Radiology

SN - 1229-6929

IS - 2

ER -