Persistent atrial fibrillation over 3 years is associated with higher recurrence after catheter ablation

Hee Tae Yu, In Soo Kim, Tae Hoon Kim, Jae Sun Uhm, Jong Youn Kim, Boyoung Joung, Moon Hyoung Lee, Hui Nam Pak

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Instruction: Longer atrial fibrillation (AF) durations have higher recurrence rates after rhythm control. However, there is limited data on the effect of the AF duration on recurrence after atrial fibrillation catheter ablation (AFCA). In the present study, we investigated the rhythm outcome of AFCA according to the AF duration based on the first electrocardiogram (ECG) diagnosis. Methods and Results: We included 1005 patients with AF (75% male, 59 ± 11 years old) who underwent AFCA and whose first ECG diagnosis time point was evident. The clinical characteristics and rhythm outcomes were compared based on the AF duration (≤3 years, n = 537; >3 years, n = 468) and AF burden (paroxysmal atrial fibrillation [PAF], n = 387; persistent atrial fibrillation [PeAF], n = 618). Longer AF durations were associated with older age (P =.020), larger left atrial size (P =.009) and a higher number of patients with hypertension (P <.001) or PeAF (P <.001). During 24 ± 22 months of follow-up, the postablation clinical recurrence rate was higher in patients with a longer AF duration (logrank P =.002). The AF recurrence rate was significantly higher in PeAF patients with an AF duration >3 years (logrank P = 0.009), but not in subjects with PAF (logrank P =.939). In a multivariate Cox regression analysis, a longer AF duration was significantly associated with a higher clinical recurrence rate after AFCA in PeAF patients (adjusted hazard ratio, 1.06; range, 1.03-0.10; P = 0.001), but not PAF. Conclusion: Although longer AF duration was associated with higher clinical recurrence rates after AFCA, the rate was significant in patients with PeAF lasting >3 years, but not in PAF patients.

Original languageEnglish
Pages (from-to)457-464
Number of pages8
JournalJournal of Cardiovascular Electrophysiology
Issue number2
Publication statusPublished - 2020 Feb 1

Bibliographical note

Funding Information:
informationThis study was supported by grants HI18C0070 and HI19C0114 from the Korea Health 21 R&D Project, Ministry of Health and Welfare and a grant NRF-2017R1A2B4003983; 2017R1C1B1008292 from the Basic Science Research Program run by the National Research Foundation of Korea (NRF).The authors like to thank John Martin for his linguistic assistance.

Publisher Copyright:
© 2020 The Authors. Journal of Cardiovascular Electrophysiology published by Wiley Periodicals, Inc.

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


Dive into the research topics of 'Persistent atrial fibrillation over 3 years is associated with higher recurrence after catheter ablation'. Together they form a unique fingerprint.

Cite this