Backgrounds: Metabolic syndrome (MetS) is an adverse health effect that can be associated with pesticide exposure. However, there are few epidemiologic studies on the relationship between pesticide use and MetS incidence. Methods: We examined the causal relationship between pesticide use and MetS incidence in a rural population. We used Data from the Korea Farmers Cohort study of 1,162 participants. Poisson regression with a robust error variance was used to calculate relative risks (RRs) and 95% confidence intervals (CIs) to estimate the relationship between pesticide exposure and MetS. Results: The incidence of MetS was 20.7%. Pesticide use increased the RR of MetS incidence. In women, we observed a low-dose effect related to MetS and pesticide exposure. Conclusion: Pesticide exposure was related to the incidence of MetS; the causal relationship differed in men and women.
Bibliographical noteFunding Information:
This work was conducted with the support of the “Cooperative Research Program for Agriculture Science & Technology Development (Project No. PJ01250901)” Rural Development Administration, Republic of Korea.
© 2019, The Korean Society of Toxicogenomics and Toxicoproteomics and Springer nature B.V.
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Pharmacology, Toxicology and Pharmaceutics(all)
- Public Health, Environmental and Occupational Health
- Health, Toxicology and Mutagenesis