pH-Tunable Thermoresponsive PEO-Based Functional Polymers with Pendant Amine Groups

Joonhee Lee; Alaina J. McGrath; Craig J. Hawker; Byeong Su Kim

doi:10.1021/acsmacrolett.6b00830

pH-Tunable Thermoresponsive PEO-Based Functional Polymers with Pendant Amine Groups

Joonhee Lee, Alaina J. McGrath, Craig J. Hawker, Byeong Su Kim

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

Thermoresponsive polymers exhibiting lower critical solution temperatures (LCSTs) in aqueous solution have garnered considerable attention for the development of smart materials. Herein, we report the synthesis and properties of pH-tunable thermoresponsive poly(ethylene oxide) (PEO)-based functional polymers bearing pendant amine groups with varying cloud points. Well-defined poly(ethylene oxide-co-allyl glycidyl ether) (P(EO-co-AGE)) copolymers were prepared via controlled anionic ring-opening copolymerization of ethylene oxide (EO) with 10 mol % of a functional allyl glycidyl ether (AGE) comonomer. Facile, modular thiol-ene click chemistry was then employed to introduce a library of different aminothiols as side chains to the initial P(EO-co-AGE) copolymer. Depending on the nature of the pendant amine groups (primary amine, dimethylamine, and diethylamine) and the hydrophobicity of the side chains (ethyl, propyl, and hexyl), the cloud points could be tuned from 44-100 °C under different pH conditions. This is the first systematic investigation into the effect of PEO copolymer side chains on cloud point, which opens up the opportunity to make new thermoresponsive polymers for a variety of smart material applications.

Original language	English
Pages (from-to)	1391-1396
Number of pages	6
Journal	ACS Macro Letters
Volume	5
Issue number	12
DOIs	https://doi.org/10.1021/acsmacrolett.6b00830
Publication status	Published - 2016 Dec 20

Bibliographical note

Funding Information:
This work was supported by the 2016 UNIST Research Fund (1.160001.01) and by the National Research Foundation of Korea (NRF; 2010-0028684). Funding is also acknowledged from the Institute for Collaborative Biotechnologies through Grant W911NF-09-0001 from the U.S. Army Research Office (A.M. and C.J.H.) with facilities support from the National Science Foundation (Materials Research Laboratory, DMR-1121053). The content of the information does not necessarily reflect the position or the policy of the U.S. government, and no official endorsement should be inferred.

Publisher Copyright:
© 2016 American Chemical Society.

All Science Journal Classification (ASJC) codes

Organic Chemistry
Polymers and Plastics
Inorganic Chemistry
Materials Chemistry

Access to Document

10.1021/acsmacrolett.6b00830

Cite this

@article{00e7b9fc44d54d28830840a9152bf813,

title = "pH-Tunable Thermoresponsive PEO-Based Functional Polymers with Pendant Amine Groups",

abstract = "Thermoresponsive polymers exhibiting lower critical solution temperatures (LCSTs) in aqueous solution have garnered considerable attention for the development of smart materials. Herein, we report the synthesis and properties of pH-tunable thermoresponsive poly(ethylene oxide) (PEO)-based functional polymers bearing pendant amine groups with varying cloud points. Well-defined poly(ethylene oxide-co-allyl glycidyl ether) (P(EO-co-AGE)) copolymers were prepared via controlled anionic ring-opening copolymerization of ethylene oxide (EO) with 10 mol % of a functional allyl glycidyl ether (AGE) comonomer. Facile, modular thiol-ene click chemistry was then employed to introduce a library of different aminothiols as side chains to the initial P(EO-co-AGE) copolymer. Depending on the nature of the pendant amine groups (primary amine, dimethylamine, and diethylamine) and the hydrophobicity of the side chains (ethyl, propyl, and hexyl), the cloud points could be tuned from 44-100 °C under different pH conditions. This is the first systematic investigation into the effect of PEO copolymer side chains on cloud point, which opens up the opportunity to make new thermoresponsive polymers for a variety of smart material applications.",

author = "Joonhee Lee and McGrath, {Alaina J.} and Hawker, {Craig J.} and Kim, {Byeong Su}",

note = "Funding Information: This work was supported by the 2016 UNIST Research Fund (1.160001.01) and by the National Research Foundation of Korea (NRF; 2010-0028684). Funding is also acknowledged from the Institute for Collaborative Biotechnologies through Grant W911NF-09-0001 from the U.S. Army Research Office (A.M. and C.J.H.) with facilities support from the National Science Foundation (Materials Research Laboratory, DMR-1121053). The content of the information does not necessarily reflect the position or the policy of the U.S. government, and no official endorsement should be inferred. Publisher Copyright: {\textcopyright} 2016 American Chemical Society.",

year = "2016",

month = dec,

day = "20",

doi = "10.1021/acsmacrolett.6b00830",

language = "English",

volume = "5",

pages = "1391--1396",

journal = "ACS Macro Letters",

issn = "2161-1653",

publisher = "American Chemical Society",

number = "12",

}

TY - JOUR

T1 - pH-Tunable Thermoresponsive PEO-Based Functional Polymers with Pendant Amine Groups

AU - Lee, Joonhee

AU - McGrath, Alaina J.

AU - Hawker, Craig J.

AU - Kim, Byeong Su

N1 - Funding Information: This work was supported by the 2016 UNIST Research Fund (1.160001.01) and by the National Research Foundation of Korea (NRF; 2010-0028684). Funding is also acknowledged from the Institute for Collaborative Biotechnologies through Grant W911NF-09-0001 from the U.S. Army Research Office (A.M. and C.J.H.) with facilities support from the National Science Foundation (Materials Research Laboratory, DMR-1121053). The content of the information does not necessarily reflect the position or the policy of the U.S. government, and no official endorsement should be inferred. Publisher Copyright: © 2016 American Chemical Society.

PY - 2016/12/20

Y1 - 2016/12/20

N2 - Thermoresponsive polymers exhibiting lower critical solution temperatures (LCSTs) in aqueous solution have garnered considerable attention for the development of smart materials. Herein, we report the synthesis and properties of pH-tunable thermoresponsive poly(ethylene oxide) (PEO)-based functional polymers bearing pendant amine groups with varying cloud points. Well-defined poly(ethylene oxide-co-allyl glycidyl ether) (P(EO-co-AGE)) copolymers were prepared via controlled anionic ring-opening copolymerization of ethylene oxide (EO) with 10 mol % of a functional allyl glycidyl ether (AGE) comonomer. Facile, modular thiol-ene click chemistry was then employed to introduce a library of different aminothiols as side chains to the initial P(EO-co-AGE) copolymer. Depending on the nature of the pendant amine groups (primary amine, dimethylamine, and diethylamine) and the hydrophobicity of the side chains (ethyl, propyl, and hexyl), the cloud points could be tuned from 44-100 °C under different pH conditions. This is the first systematic investigation into the effect of PEO copolymer side chains on cloud point, which opens up the opportunity to make new thermoresponsive polymers for a variety of smart material applications.

AB - Thermoresponsive polymers exhibiting lower critical solution temperatures (LCSTs) in aqueous solution have garnered considerable attention for the development of smart materials. Herein, we report the synthesis and properties of pH-tunable thermoresponsive poly(ethylene oxide) (PEO)-based functional polymers bearing pendant amine groups with varying cloud points. Well-defined poly(ethylene oxide-co-allyl glycidyl ether) (P(EO-co-AGE)) copolymers were prepared via controlled anionic ring-opening copolymerization of ethylene oxide (EO) with 10 mol % of a functional allyl glycidyl ether (AGE) comonomer. Facile, modular thiol-ene click chemistry was then employed to introduce a library of different aminothiols as side chains to the initial P(EO-co-AGE) copolymer. Depending on the nature of the pendant amine groups (primary amine, dimethylamine, and diethylamine) and the hydrophobicity of the side chains (ethyl, propyl, and hexyl), the cloud points could be tuned from 44-100 °C under different pH conditions. This is the first systematic investigation into the effect of PEO copolymer side chains on cloud point, which opens up the opportunity to make new thermoresponsive polymers for a variety of smart material applications.

UR - http://www.scopus.com/inward/record.url?scp=85007020957&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85007020957&partnerID=8YFLogxK

U2 - 10.1021/acsmacrolett.6b00830

DO - 10.1021/acsmacrolett.6b00830

M3 - Article

AN - SCOPUS:85007020957

SN - 2161-1653

VL - 5

SP - 1391

EP - 1396

JO - ACS Macro Letters

JF - ACS Macro Letters

IS - 12

ER -

pH-Tunable Thermoresponsive PEO-Based Functional Polymers with Pendant Amine Groups

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this