Pharaoh ant (Monomorium pharaonis): Newly identified important inhalant allergens in bronchial asthma

Cheol Woo Kim, Deok In Kim, Soo Young Choi, Jung Won Park, Chein Soo Hong

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The nonstinging house ant, Monomorium pharaonis (pharaoh ant), was recently identified as a cause of respiratory allergy. This study was performed to evaluate the extent of sensitization to pharaoh ant, and its clinical significance in asthmatic patients. We carried out skin prick tests in 318 patients with asthma. Specific IgE (sIgE) to pharaoh ant was measured by ELISA, and cross-reactivity was evaluated by ELISA inhibition tests. Bronchial provocation testing was performed using pharaoh ant extracts. Fifty-eight (18.2%) of 318 patients showed positive skin responses to pharaoh ant, and 25 (7.9%) had an isolated response to pharaoh ant. Positive skin responses to pharaoh ant were significantly higher among patients with non-atopic asthma than among those with atopic asthma (26.0% vs. 14.9%, p<0.05). There was significant correlation between sIgE level and skin responses to pharaoh ant (rho=0.552, p<0.001). The ELISA inhibition tests indicated that pharaoh ant allergens had various pattern of cross-reactivity to house dust mites and cockroaches. Bronchial provocation tests to pharaoh ant were conducted for 9 patients, and eight showed typical asthmatic reactions. In conclusion, pharaoh ant is an important source of aeroallergens, and it should be included in the skin test battery for screening the causative allergens in patients with asthma.

Original languageEnglish
Pages (from-to)390-396
Number of pages7
JournalJournal of Korean medical science
Volume20
Issue number3
DOIs
Publication statusPublished - 2005 Jun

Fingerprint

Ants
Allergens
Asthma
Enzyme-Linked Immunosorbent Assay
Skin Tests
Skin
Immunoglobulin E
Bronchial Provocation Tests
Pyroglyphidae
Cockroaches
Hypersensitivity

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kim, Cheol Woo ; Kim, Deok In ; Choi, Soo Young ; Park, Jung Won ; Hong, Chein Soo. / Pharaoh ant (Monomorium pharaonis) : Newly identified important inhalant allergens in bronchial asthma. In: Journal of Korean medical science. 2005 ; Vol. 20, No. 3. pp. 390-396.
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Pharaoh ant (Monomorium pharaonis) : Newly identified important inhalant allergens in bronchial asthma. / Kim, Cheol Woo; Kim, Deok In; Choi, Soo Young; Park, Jung Won; Hong, Chein Soo.

In: Journal of Korean medical science, Vol. 20, No. 3, 06.2005, p. 390-396.

Research output: Contribution to journalArticle

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