Pharmacokinetics of indinavir in Koreans and Caucasians

Jun Yong Choi; Kyung Hee Chang; Yoon Soo Park; Cheong Ho Cho; So Youn Shin; Young Goo Song; June Myung Kim

doi:10.1080/00365540410019697

Pharmacokinetics of indinavir in Koreans and Caucasians

Jun Yong Choi, Kyung Hee Chang, Yoon Soo Park, Cheong Ho Cho, So Youn Shin, Young Goo Song, June Myung Kim

Department of Internal Medicine

Research output: Contribution to journal › Article

1 Citation (Scopus)

Abstract

We evaluated whether the pharmacokinetic parameters of indinavir differ in Koreans and Caucasians. Indinavir was administered orally to 8 healthy Koreans and 4 healthy Caucasians, and plasma indinavir levels were quantified by high performance liquid chromatography. No significant differences were observed in terms of its pharmacokinetic parameters; however, the AUC difference between the 2 groups may be significant for larger sample sizes.

Original language	English
Pages (from-to)	307-309
Number of pages	3
Journal	Scandinavian Journal of Infectious Diseases
Volume	36
Issue number	4
DOIs	https://doi.org/10.1080/00365540410019697
Publication status	Published - 2004

Bibliographical note

Funding Information:
This study was supported by the BK21 Project for Medical Sciences, Yonsei University.

All Science Journal Classification (ASJC) codes

Immunology and Microbiology(all)
Microbiology (medical)
Infectious Diseases

Access to Document

10.1080/00365540410019697

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abstract = "We evaluated whether the pharmacokinetic parameters of indinavir differ in Koreans and Caucasians. Indinavir was administered orally to 8 healthy Koreans and 4 healthy Caucasians, and plasma indinavir levels were quantified by high performance liquid chromatography. No significant differences were observed in terms of its pharmacokinetic parameters; however, the AUC difference between the 2 groups may be significant for larger sample sizes.",

author = "Choi, {Jun Yong} and Chang, {Kyung Hee} and Park, {Yoon Soo} and Cho, {Cheong Ho} and Shin, {So Youn} and Song, {Young Goo} and Kim, {June Myung}",

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AU - Chang, Kyung Hee

AU - Park, Yoon Soo

AU - Cho, Cheong Ho

AU - Shin, So Youn

AU - Song, Young Goo

AU - Kim, June Myung

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