Photosensitizing hollow nanocapsules for combination cancer therapy

Kyung Jin Son, Hee Jae Yoon, Joo Ho Kim, Woo Dong Jang, Yeol Lee, Won Gun Koh

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Many layers make light work: Layer-by-layer (LbL) self-assembly of a dendritic porphyrin (red; see picture) and poly(allylamine hydrochloride) (blue) on polystyrene nanoparticles followed by removal of the polystyrene core produces multifunctional hollow nanocapsules. These species can be both loaded with anticancer drugs and used in photodynamic therapy (PDT) and therefore have potential in combined cancer therapy.

Original languageEnglish
Pages (from-to)11968-11971
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number50
DOIs
Publication statusPublished - 2011 Dec 9

Fingerprint

Nanocapsules
Polystyrenes
Photodynamic therapy
Porphyrins
Self assembly
Nanoparticles
Pharmaceutical Preparations
polyallylamine

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Cite this

Son, Kyung Jin ; Yoon, Hee Jae ; Kim, Joo Ho ; Jang, Woo Dong ; Lee, Yeol ; Koh, Won Gun. / Photosensitizing hollow nanocapsules for combination cancer therapy. In: Angewandte Chemie - International Edition. 2011 ; Vol. 50, No. 50. pp. 11968-11971.
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Photosensitizing hollow nanocapsules for combination cancer therapy. / Son, Kyung Jin; Yoon, Hee Jae; Kim, Joo Ho; Jang, Woo Dong; Lee, Yeol; Koh, Won Gun.

In: Angewandte Chemie - International Edition, Vol. 50, No. 50, 09.12.2011, p. 11968-11971.

Research output: Contribution to journalArticle

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