Plaque ruptures in stable angina pectoris compared with acute coronary syndrome

Myeong Ki Hong, Gary S. Mintz, Cheol Whan Lee, Kyoung Min Park, Bong Ki Lee, Young Hak Kim, Duk Hyun Kang, Sang Sig Cheong, Jae Kwan Song, Jae Joong Kim, Seong Wook Park, Seung Jung Park

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14 Citations (Scopus)

Abstract

Background: Plaque rupture is more frequently observed in patients with acute coronary syndrome (ACS) rather than in patients with stable angina pectoris (SAP). Consequently, studies regarding plaque rupture, which occurred in SAP patients, are rare. Therefore, we evaluated the frequency and axial location of plaque ruptures in SAP patients and compared them with those in ACS patients. Methods: Three hundred ninety-two patients (231 ACS and 161 SAP patients) who were scheduled for coronary intervention underwent three-vessel intravascular ultrasound (IVUS) study. IVUS criteria for plaque rupture were a plaque contained a cavity that communicated with the lumen with an overlying residual fibrous cap fragment. Using motorized IVUS transducer pullback in all three coronary arteries, the distance between each coronary plaque rupture segment and the respective coronary ostium was measured. Results: Plaque ruptures were detected in 206 of 392 patients who underwent three-vessel intravascular ultrasound examination. At least one plaque rupture in any coronary artery was noted in 48 (30%) SAP and 158 (68%) ACS patients (p < 0.001). In both ACS and SAP patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery. Conclusions: At least one plaque rupture in any coronary artery was noted in 30% of SAP patients. Like in ACS patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery in SAP patients.

Original languageEnglish
Pages (from-to)78-82
Number of pages5
JournalInternational Journal of Cardiology
Volume114
Issue number1
DOIs
Publication statusPublished - 2007 Jan 2

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Stable Angina
Acute Coronary Syndrome
Rupture
Coronary Vessels
Arteries
Transducers

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Hong, Myeong Ki ; Mintz, Gary S. ; Lee, Cheol Whan ; Park, Kyoung Min ; Lee, Bong Ki ; Kim, Young Hak ; Kang, Duk Hyun ; Cheong, Sang Sig ; Song, Jae Kwan ; Kim, Jae Joong ; Park, Seong Wook ; Park, Seung Jung. / Plaque ruptures in stable angina pectoris compared with acute coronary syndrome. In: International Journal of Cardiology. 2007 ; Vol. 114, No. 1. pp. 78-82.
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title = "Plaque ruptures in stable angina pectoris compared with acute coronary syndrome",
abstract = "Background: Plaque rupture is more frequently observed in patients with acute coronary syndrome (ACS) rather than in patients with stable angina pectoris (SAP). Consequently, studies regarding plaque rupture, which occurred in SAP patients, are rare. Therefore, we evaluated the frequency and axial location of plaque ruptures in SAP patients and compared them with those in ACS patients. Methods: Three hundred ninety-two patients (231 ACS and 161 SAP patients) who were scheduled for coronary intervention underwent three-vessel intravascular ultrasound (IVUS) study. IVUS criteria for plaque rupture were a plaque contained a cavity that communicated with the lumen with an overlying residual fibrous cap fragment. Using motorized IVUS transducer pullback in all three coronary arteries, the distance between each coronary plaque rupture segment and the respective coronary ostium was measured. Results: Plaque ruptures were detected in 206 of 392 patients who underwent three-vessel intravascular ultrasound examination. At least one plaque rupture in any coronary artery was noted in 48 (30{\%}) SAP and 158 (68{\%}) ACS patients (p < 0.001). In both ACS and SAP patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery. Conclusions: At least one plaque rupture in any coronary artery was noted in 30{\%} of SAP patients. Like in ACS patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery in SAP patients.",
author = "Hong, {Myeong Ki} and Mintz, {Gary S.} and Lee, {Cheol Whan} and Park, {Kyoung Min} and Lee, {Bong Ki} and Kim, {Young Hak} and Kang, {Duk Hyun} and Cheong, {Sang Sig} and Song, {Jae Kwan} and Kim, {Jae Joong} and Park, {Seong Wook} and Park, {Seung Jung}",
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Hong, MK, Mintz, GS, Lee, CW, Park, KM, Lee, BK, Kim, YH, Kang, DH, Cheong, SS, Song, JK, Kim, JJ, Park, SW & Park, SJ 2007, 'Plaque ruptures in stable angina pectoris compared with acute coronary syndrome', International Journal of Cardiology, vol. 114, no. 1, pp. 78-82. https://doi.org/10.1016/j.ijcard.2006.01.008

Plaque ruptures in stable angina pectoris compared with acute coronary syndrome. / Hong, Myeong Ki; Mintz, Gary S.; Lee, Cheol Whan; Park, Kyoung Min; Lee, Bong Ki; Kim, Young Hak; Kang, Duk Hyun; Cheong, Sang Sig; Song, Jae Kwan; Kim, Jae Joong; Park, Seong Wook; Park, Seung Jung.

In: International Journal of Cardiology, Vol. 114, No. 1, 02.01.2007, p. 78-82.

Research output: Contribution to journalArticle

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T1 - Plaque ruptures in stable angina pectoris compared with acute coronary syndrome

AU - Hong, Myeong Ki

AU - Mintz, Gary S.

AU - Lee, Cheol Whan

AU - Park, Kyoung Min

AU - Lee, Bong Ki

AU - Kim, Young Hak

AU - Kang, Duk Hyun

AU - Cheong, Sang Sig

AU - Song, Jae Kwan

AU - Kim, Jae Joong

AU - Park, Seong Wook

AU - Park, Seung Jung

PY - 2007/1/2

Y1 - 2007/1/2

N2 - Background: Plaque rupture is more frequently observed in patients with acute coronary syndrome (ACS) rather than in patients with stable angina pectoris (SAP). Consequently, studies regarding plaque rupture, which occurred in SAP patients, are rare. Therefore, we evaluated the frequency and axial location of plaque ruptures in SAP patients and compared them with those in ACS patients. Methods: Three hundred ninety-two patients (231 ACS and 161 SAP patients) who were scheduled for coronary intervention underwent three-vessel intravascular ultrasound (IVUS) study. IVUS criteria for plaque rupture were a plaque contained a cavity that communicated with the lumen with an overlying residual fibrous cap fragment. Using motorized IVUS transducer pullback in all three coronary arteries, the distance between each coronary plaque rupture segment and the respective coronary ostium was measured. Results: Plaque ruptures were detected in 206 of 392 patients who underwent three-vessel intravascular ultrasound examination. At least one plaque rupture in any coronary artery was noted in 48 (30%) SAP and 158 (68%) ACS patients (p < 0.001). In both ACS and SAP patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery. Conclusions: At least one plaque rupture in any coronary artery was noted in 30% of SAP patients. Like in ACS patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery in SAP patients.

AB - Background: Plaque rupture is more frequently observed in patients with acute coronary syndrome (ACS) rather than in patients with stable angina pectoris (SAP). Consequently, studies regarding plaque rupture, which occurred in SAP patients, are rare. Therefore, we evaluated the frequency and axial location of plaque ruptures in SAP patients and compared them with those in ACS patients. Methods: Three hundred ninety-two patients (231 ACS and 161 SAP patients) who were scheduled for coronary intervention underwent three-vessel intravascular ultrasound (IVUS) study. IVUS criteria for plaque rupture were a plaque contained a cavity that communicated with the lumen with an overlying residual fibrous cap fragment. Using motorized IVUS transducer pullback in all three coronary arteries, the distance between each coronary plaque rupture segment and the respective coronary ostium was measured. Results: Plaque ruptures were detected in 206 of 392 patients who underwent three-vessel intravascular ultrasound examination. At least one plaque rupture in any coronary artery was noted in 48 (30%) SAP and 158 (68%) ACS patients (p < 0.001). In both ACS and SAP patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery. Conclusions: At least one plaque rupture in any coronary artery was noted in 30% of SAP patients. Like in ACS patients, plaque ruptures were clustered mainly in the proximal segments of the left anterior descending artery and in the proximal and distal segments of the right coronary artery in SAP patients.

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