Platelet-enriched fibrin glue and platelet-rich plasma in the repair of bone defects adjacent to titanium dental implants

Tae Min You, Byung Ho Choi, Shi Jiang Zhu, Jae Hyung Jung, Seoung Ho Lee, Jin Young Huh, Hyun Jung Lee, Jingxu Li

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Purpose: The aim of this study was to compare the effects of platelet-enriched fibrin glue and platelet-rich plasma (PRP) on the repair of bone defects adjacent to titanium dental implants. Materials and Methods: In 6 mongrel dogs, 3 screw-shaped titanium dental implants per dog were placed into the osteotomy sites in the tibia. Before implantation, a standardized gap (2.0 mm) was created between the implant surface and the surrounding bone walls. Six gaps were left empty (control group), 6 gaps were filled with autogenous particulate bone mixed with PRP (PRP group), and 6 gaps were filled with autogenous particulate bone mixed with platelet-enriched fibrin glue (fibrin glue group). Results: After 6 weeks, the bone-implant contact was 59.7% in the fibrin glue group, 29.2% in the PRP group, and 10.2% in the control defects; this difference was statistically significant (P < .05). Discussion and Conclusion: Greater bone-implant contact was achieved with platelet-enriched fibrin glue than with PRP. The results indicate that platelet-enriched fibrin glue can induce a stronger peri-implant bone reaction than PRP in the treatment of bone defects adjacent to titanium dental implants.

Original languageEnglish
Pages (from-to)417-422
Number of pages6
JournalInternational Journal of Oral and Maxillofacial Implants
Volume22
Issue number3
Publication statusPublished - 2007 May 1

All Science Journal Classification (ASJC) codes

  • Oral Surgery

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