Pluripotent stem cell therapy for cardiac regeneration

Kiwon Ban, Jaemin Byun, Sangsung Kim, Sukwon Koh, Young Sup Yoon

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Heart failure is a leading cause of death worldwide, accounting for more than 800,000 deaths per year on average equivalent to 1 death every 39 s (Members et al. 2012). Each year, nearly 6 million patients die from heart failure in the United States. Regardless of its clinical significance, current therapies, including surgical and pharmacological interventions, are only capable of delaying the progression of this detrimental disease (Lopez et al. 2006). Particularly, myocardial infarction (MI) is one of the major causes of mortality, and in cases where it does not lead to sudden death, it damages a majority portion of myocardium of the heart leading to a condition in which almost half of affected patients die within 1 year from the onset of symptoms due to diminished cardiac contractile function to below a critical threshold (Jessup and Brozena 2003).

Original languageEnglish
Title of host publicationCardiovascular Diseases
Subtitle of host publicationNutritional and Therapeutic Interventions
PublisherCRC Press
Pages235-254
Number of pages20
ISBN (Electronic)9781439882016
ISBN (Print)9781439882009
Publication statusPublished - 2013 Jan 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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    Ban, K., Byun, J., Kim, S., Koh, S., & Yoon, Y. S. (2013). Pluripotent stem cell therapy for cardiac regeneration. In Cardiovascular Diseases: Nutritional and Therapeutic Interventions (pp. 235-254). CRC Press.