Population structure and distribution of virulence-related genes of Bacteroides fragilis isolates from Korea and Japan

Kwan Soo Ko, Tomomi Kuwahara, Kyungwon Lee, Yoon Hoh Kook

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Sequences for rpoB, gyrB, pdiA, and ompA were determined from 63 Bacteroides fragilis isolates, which were from Korea and Japan and include 4 reference strains. All 4 gene sequences supported clear separation of the cfi+ group from the cfi- group. Combined sequences of the 60 division I isolates (cfi-) produced 45 different clones. Apparent discordance of gene trees, index of association, maximum likelihood test, and homoplasy ratio all supported a high frequency of recombination. There was no association between the presence of virulence-related genes and phylogenetic clustering in any gene tree.

Original languageEnglish
Pages (from-to)340-343
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume64
Issue number3
DOIs
Publication statusPublished - 2009 Jul

Bibliographical note

Funding Information:
This work was supported in part by the BK21 Project for Medicine, Dentistry, and Pharmacy in Seoul National University, Seoul, South Korea.

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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