Sequences for rpoB, gyrB, pdiA, and ompA were determined from 63 Bacteroides fragilis isolates, which were from Korea and Japan and include 4 reference strains. All 4 gene sequences supported clear separation of the cfi+ group from the cfi- group. Combined sequences of the 60 division I isolates (cfi-) produced 45 different clones. Apparent discordance of gene trees, index of association, maximum likelihood test, and homoplasy ratio all supported a high frequency of recombination. There was no association between the presence of virulence-related genes and phylogenetic clustering in any gene tree.
|Number of pages||4|
|Journal||Diagnostic Microbiology and Infectious Disease|
|Publication status||Published - 2009 Jul|
Bibliographical noteFunding Information:
This work was supported in part by the BK21 Project for Medicine, Dentistry, and Pharmacy in Seoul National University, Seoul, South Korea.
All Science Journal Classification (ASJC) codes
- Microbiology (medical)
- Infectious Diseases