Post-infectious irritable bowel syndrome in patients with Shigella infection

Sangwon Ji, Hyojin Park, Dokyong Lee, Young Koo Song, Jae Phil Choi, Sang In Lee

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

Background and Aims: Bacterial gastroenteritis has been known as a risk factor of irritable bowel syndrome (IBS). Several risk factors of post-infectious IBS (PI-IBS) have been documented. The aims of this study were to verify the role of bacterial gastroenteritis in the development of IBS and the risk factors for the development of PI-IBS. The clinical course of PI-IBS was also investigated. Methods: We recruited 143 patients with shigellosis during its outbreak and 113 controls. Both groups were followed up for 12 months. Bowel symptoms were evaluated by use of questionnaires at 3, 6 and 12 months after the initial recruitment. Results: Complete data were obtained from 101 patients (70.6%) and 102 healthy controls (90.3%). At 12 months, 15 patients and six controls had IBS (adjusted OR; 2.9, 95% CI; 1.1-7.9). Of the 15 patients, five had IBS symptoms consistently for 12 months, three did not have IBS symptoms initially and seven had fluctuating bowel symptoms. The duration of diarrhea was an independent risk factor of PI-IBS. Conclusions: Bacterial gastroenteritis is a risk factor of IBS and the duration of diarrhea as the index of severity of initial illness is an independent risk factor of PI-IBS. The clinical course of PI-IBS is variable over the 1 year of follow-up.

Original languageEnglish
Pages (from-to)381-386
Number of pages6
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume20
Issue number3
DOIs
Publication statusPublished - 2005 Mar

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Shigella
Irritable Bowel Syndrome
Infection
Gastroenteritis
Severity of Illness Index
Diarrhea
Bacillary Dysentery
Disease Outbreaks

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Ji, Sangwon ; Park, Hyojin ; Lee, Dokyong ; Song, Young Koo ; Choi, Jae Phil ; Lee, Sang In. / Post-infectious irritable bowel syndrome in patients with Shigella infection. In: Journal of Gastroenterology and Hepatology (Australia). 2005 ; Vol. 20, No. 3. pp. 381-386.
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Post-infectious irritable bowel syndrome in patients with Shigella infection. / Ji, Sangwon; Park, Hyojin; Lee, Dokyong; Song, Young Koo; Choi, Jae Phil; Lee, Sang In.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 20, No. 3, 03.2005, p. 381-386.

Research output: Contribution to journalArticle

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