Postnatal risk factors of retinopathy of prematurity

Tae Im Kim, Joonhong Sohn, Soo Young Pi, Young Hee Yoon

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Abstract

To investigate the postnatal risk factors of retinopathy of prematurity (ROP), we analysed demographic and clinical data abstracted from the medical records of 425 premature babies who were examined for ROP between January 1994 and December 1998 at Asan Medical Centre, Seoul, Korea. ROP developed in 20.7% of the cases studied. A gestational age (GA) of ≤28 weeks and birthweight (BW) of ≤1000 g were the most significant risk factors. Ventilator care for ≥48 h, apnoea, and use of surfactant independently increased the incidence of ROP. Furthermore, frequent apnoeic attacks increased the progression of pre-threshold ROP to threshold ROP. Therefore, as well as GA and BW, apnoea, prolonged use of a ventilator, and surfactant therapy are significant independent risk factors for ROP. In addition, apnoea may not only increase the risk of developing ROP, but may also worsen pre-existing ROP.

Original languageEnglish
Pages (from-to)130-134
Number of pages5
JournalPaediatric and Perinatal Epidemiology
Volume18
Issue number2
DOIs
Publication statusPublished - 2004 Mar 1

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All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Pediatrics, Perinatology, and Child Health

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