Low anterior resection syndrome (LARS) refers to a disturbance of bowel function that commonly manifests within 1 month after rectal cancer surgery. A low level of anastomosis and chemoradiotherapy have been consistently found to be risk factors for developing LARS. Thorough history taking and physical examination with adjunctive procedures are essential when evaluating patients with LARS. Anorectal manometry, fecoflowmetry, and validated questionnaires are important tools for assessing the quality of life of patients with LARS. Conservative management (medical, physiotherapy, transanal irrigation), invasive procedures (neuromodulation), and multimodal therapy are the mainstay of treatment for patients with LARS. A stoma could be considered when other treatment modalities have failed. An initial meticulous surgical procedure for rectal cancer, creation of a neorectal reservoir during anastomosis, and proper exercise of the anal sphincter muscle (Kegel's maneuver) are essential to combat LARS. Pretreatment counseling is a crucial step for patients who have risk factors for developing LARS.
|Number of pages||7|
|Journal||Annals of Coloproctology|
|Publication status||Published - 2019|
Bibliographical noteFunding Information:
This research was supported by a grant (NRF-2017R1D1A3-B03032301) of the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education.
© 2019 The Korean Society of Coloproctology
All Science Journal Classification (ASJC) codes