Practice patterns of Korean urologists for screening and managing prostate cancer according to PSA level

Mun Su Chung, Seung Hwan Lee, Dong Hoon Lee, Se Joong Kim, Choung Soo Kim, Kyu Sung Lee, Jae Il Jung, Sae Woong Kim, Yil Seob Lee, Byung Ha Chung

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Purpose: There are still debates on the benefit of mass screening for prostate cancer (PCA) by prostate specific antigen (PSA) testing, and on systemized surveillance protocols according to PSA level. Furthermore, there is a paucity of literature on current practice patterns according to PSA level in the Korean urologic field. Here, we report the results of a nationwide, multicenter, retrospective chart-review study. Materials and Methods: Overall 2122 Korean men (>40 years old, PSA >2.5 ng/mL) were included in our study (from 122 centers, in 2008). The primary endpoint was to analyze the rate of prostate biopsy according to PSA level. Secondary aims were to analyze the detection rate of PCA, the clinical features of patients, and the status of surveillance for PCA according to PSA level. Results: The rate of prostate biopsy was 7.1%, 26.3%, 54.2%, and 64.3% according to PSA levels of 2.5-3.0, 3.0-4.0, 4.0-10.0, and >10.0 ng/mL, respectively, and the PCA detection rate was 16.0%, 22.2%, 20.2%, and 59.6%, respectively. At a PSA level >4.0 ng/mL, we found a lower incidence of prostate biopsy in local clinics than in general hospitals (21.6% vs. 66.2%, respectively). A significant proportion (16.6%) of patients exhibited high Gleason scores (≥8) even in the group with low PSA values (2.5-4.0 ng/mL). Conclusion: We believe that the results from this nationwide study might provide an important database for the establishment of practical guidelines for the screening and management of PCA in Korean populations.

Original languageEnglish
Pages (from-to)1136-1141
Number of pages6
JournalYonsei medical journal
Volume53
Issue number6
DOIs
Publication statusPublished - 2012 Nov

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Fingerprint Dive into the research topics of 'Practice patterns of Korean urologists for screening and managing prostate cancer according to PSA level'. Together they form a unique fingerprint.

  • Cite this

    Chung, M. S., Lee, S. H., Lee, D. H., Kim, S. J., Kim, C. S., Lee, K. S., Jung, J. I., Kim, S. W., Lee, Y. S., & Chung, B. H. (2012). Practice patterns of Korean urologists for screening and managing prostate cancer according to PSA level. Yonsei medical journal, 53(6), 1136-1141. https://doi.org/10.3349/ymj.2012.53.6.1136