To evaluate the association between pre-natal and post-natal exposure to pet ownership and lung function in children, a cross-sectional study named Seven Northeastern Cities (SNEC) study was conducted. In this study, children's lung function including the forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), maximal mid-expiratory flow (MMEF), and peak expiratory flow (PEF) were measured by spirometers, and pet ownership situations were collected by questionnaire. Analyzed by multiple logistic regression and generalized linear modeling, we found that for all subjects, pet exposure in the first 2 years of life was significantly associated with lung function impairment of FVC<85% predicted (adjusted odds ratio [aOR]=1.28; 95% confidence interval [CI]: 1.01, 1.63). For current pet exposure, the increased odds of lung function impairment ranged from 35% (aOR=1.35; 95%CI: 1.12, 1.62) for FVC<85% predicted to 57% (aOR=1.57; 95%CI: 1.29, 1.93) for FEV1<85% predicted. The in utero exposure was not related to lung function impairment. Compared with other pets, higher odds were observed among children with dogs. When stratified by gender, girls with current pet exposure were more likely to have lung function impairment than boys. It implies self-reported exposures to pets were negatively associated with lung function among the children under study.
Bibliographical noteFunding Information:
National Program on Key Research Project of China, Grant/Award Number: 2016YFC0207000; Fundamental Research Funds for the Central Universities, Grant/ Award Number: 16ykzd02; the Guangdong Province Natural Science Foundation, Grant/ Award Number: 2014A050503027.
This work was supported by Grants from the National Program on Key Research Project of China (No. 2016YFC0207000), the Fundamental Research Funds for the Central Universities (No. 16ykzd02), and the GuangdongProvinceNaturalScienceFoundation(No.2014A050503027). The participating families are gratefully acknowledged for their collaboration. We also thank the SNEC study group.
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
All Science Journal Classification (ASJC) codes
- Environmental Engineering
- Building and Construction
- Public Health, Environmental and Occupational Health