TY - JOUR
T1 - Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold
AU - Han, Inho
AU - Vagaska, Barbora
AU - Lee, Dae Hyung
AU - Park, Bong Joo
AU - Shin, Seung Woo
AU - Kim, Jeong Koo
AU - Lee, Seung Jin
AU - Park, Jong Chul
PY - 2011/7
Y1 - 2011/7
N2 - Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future.
AB - Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future.
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U2 - 10.1007/s13233-011-0701-7
DO - 10.1007/s13233-011-0701-7
M3 - Article
AN - SCOPUS:79960053950
SN - 1598-5032
VL - 19
SP - 711
EP - 715
JO - Macromolecular Research
JF - Macromolecular Research
IS - 7
ER -