Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold

Inho Han, Barbora Vagaska, Dae Hyung Lee, Bong Joo Park, Seung Woo Shin, Jeong Koo Kim, Seung Jin Lee, Jong Chul Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future.

Original languageEnglish
Pages (from-to)711-715
Number of pages5
JournalMacromolecular Research
Volume19
Issue number7
DOIs
Publication statusPublished - 2011 Jul 1

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All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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