Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold

Inho Han, Barbora Vagaska, Dae Hyung Lee, Bong Joo Park, Seung Woo Shin, Jeong Koo Kim, Seung Jin Lee, Jong Chul Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future.

Original languageEnglish
Pages (from-to)711-715
Number of pages5
JournalMacromolecular Research
Volume19
Issue number7
DOIs
Publication statusPublished - 2011 Jul 1

Fingerprint

Helium
Glow discharges
Scaffolds
Atmospheric pressure
Wetting
Tissue regeneration
Cytotoxicity
Processing
Hydroxyl Radical
Culture Media
Polymers

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

Cite this

Han, Inho ; Vagaska, Barbora ; Lee, Dae Hyung ; Park, Bong Joo ; Shin, Seung Woo ; Kim, Jeong Koo ; Lee, Seung Jin ; Park, Jong Chul. / Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold. In: Macromolecular Research. 2011 ; Vol. 19, No. 7. pp. 711-715.
@article{87099a7de2b5453c87b25c92f55f5d2f,
title = "Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold",
abstract = "Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future.",
author = "Inho Han and Barbora Vagaska and Lee, {Dae Hyung} and Park, {Bong Joo} and Shin, {Seung Woo} and Kim, {Jeong Koo} and Lee, {Seung Jin} and Park, {Jong Chul}",
year = "2011",
month = "7",
day = "1",
doi = "10.1007/s13233-011-0701-7",
language = "English",
volume = "19",
pages = "711--715",
journal = "Macromolecular Research",
issn = "1598-5032",
publisher = "Polymer Society of Korea",
number = "7",

}

Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold. / Han, Inho; Vagaska, Barbora; Lee, Dae Hyung; Park, Bong Joo; Shin, Seung Woo; Kim, Jeong Koo; Lee, Seung Jin; Park, Jong Chul.

In: Macromolecular Research, Vol. 19, No. 7, 01.07.2011, p. 711-715.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold

AU - Han, Inho

AU - Vagaska, Barbora

AU - Lee, Dae Hyung

AU - Park, Bong Joo

AU - Shin, Seung Woo

AU - Kim, Jeong Koo

AU - Lee, Seung Jin

AU - Park, Jong Chul

PY - 2011/7/1

Y1 - 2011/7/1

N2 - Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future.

AB - Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future.

UR - http://www.scopus.com/inward/record.url?scp=79960053950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960053950&partnerID=8YFLogxK

U2 - 10.1007/s13233-011-0701-7

DO - 10.1007/s13233-011-0701-7

M3 - Article

AN - SCOPUS:79960053950

VL - 19

SP - 711

EP - 715

JO - Macromolecular Research

JF - Macromolecular Research

SN - 1598-5032

IS - 7

ER -