Predicting lymph node metastasis in patients with papillary thyroid carcinoma by vascular index on power Doppler ultrasound

Ji Hye Lee, Hyun Joo Shin, Jung Hyun Yoon, Eunkyung Kim, Hee Jung Moon, Hye Sun Lee, Hyeongju Kwon, jinyoung kwak

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: For patients with papillary thyroid carcinoma (PTC), lymph node metastasis is associated with an increased recurrence rate. The purpose of this study was to investigate whether the vascular endothelial growth factor (VEGF), microvessel density (MVD), and vascular index (VI) can predict lymph node metastasis in patients with PTC. Methods: From January 2011 to October 2011, 202 patients with PTCs underwent preoperative staging ultrasound evaluation. To evaluate vascularity, we measured the VI, VEGF expression, and MVD. Results: The VI was significantly correlated with MVD (p =.009). On multivariate analysis, young age showed a significant correlation with lymph node metastasis (p <.001; p <.001; p <.001). However, the other clinicopathologic features, VEGF, MVD, and VI failed to show any significant correlations with lymph node metastasis. Conclusion: Although the VI showed significant correlation with MVD, it was not significantly correlated to lymph node metastasis.

Original languageEnglish
Pages (from-to)334-340
Number of pages7
JournalHead and Neck
Volume39
Issue number2
DOIs
Publication statusPublished - 2017 Feb 1

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Doppler Ultrasonography
Microvessels
Blood Vessels
Lymph Nodes
Neoplasm Metastasis
Vascular Endothelial Growth Factor A
Factor IX
Multivariate Analysis
Papillary Thyroid cancer
Recurrence

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Lee, Ji Hye ; Shin, Hyun Joo ; Yoon, Jung Hyun ; Kim, Eunkyung ; Moon, Hee Jung ; Lee, Hye Sun ; Kwon, Hyeongju ; kwak, jinyoung. / Predicting lymph node metastasis in patients with papillary thyroid carcinoma by vascular index on power Doppler ultrasound. In: Head and Neck. 2017 ; Vol. 39, No. 2. pp. 334-340.
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Predicting lymph node metastasis in patients with papillary thyroid carcinoma by vascular index on power Doppler ultrasound. / Lee, Ji Hye; Shin, Hyun Joo; Yoon, Jung Hyun; Kim, Eunkyung; Moon, Hee Jung; Lee, Hye Sun; Kwon, Hyeongju; kwak, jinyoung.

In: Head and Neck, Vol. 39, No. 2, 01.02.2017, p. 334-340.

Research output: Contribution to journalArticle

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AU - Yoon, Jung Hyun

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AU - Moon, Hee Jung

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