Prediction of left ventricular dilatation with thallium-201 SPET imaging after primary angioplasty in patients with acute myocardial infarction

Joon Choi, Dae Moon, Cheol Lee, Jung Shin, Seong Wook Park, Myeong Ki Hong, Jae Kwan Song, Seung Jung Park, Hee Lee

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Progressive ventricular dilatation is an important prognostic factor in patients with acute myocardial infarction. We evaluated clinical, angiographic, echocardiographic and thallium-201 single-photon emission tomography (SPET) imaging variables predictive of the change in left ventricular volume during a 7-month follow-up period after primary angioplasty in patients with acute myocardial infarction. Thirty-six patients with first acute myocardial infarction treated with primary angioplasty within 12 h of onset underwent 201Tl SPET imaging (5.8±2.1 days after angioplasty). Changes in left ventricular volume were assessed over the 7-month period. The left ventricle dilated significantly after angioplasty (P<0.001). Multivariate analysis revealed that the number of segments with 201Tl uptake <40% of peak activity was a single independent predictor of increase in end-diastolic volume index between 1 week and 7 months (R2=0.41, P<0.001). The presence of two or more segments with 201Tl uptake <40% predicted an increase in end-diastolic volume index of ≥6 ml/m2 with positive and negative predictive values of 85% (17/20) and 75% (12/16), respectively. It is concluded that, following primary angioplasty in patients with acute myocardial infarction, the extent of myocardial infarction assessed by 201Tl SPET can identify those who will develop ventricular dilatation during the subsequent 7 months.

Original languageEnglish
Pages (from-to)728-734
Number of pages7
JournalEuropean Journal of Nuclear Medicine
Volume29
Issue number6
DOIs
Publication statusPublished - 2002

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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