Predictive capability of anorectal physiologic tests for unfavorable outcomes following biofeedback therapy in dyssynergic defecation

Jae Kook Shin, Jae Hee Cheon, Eun Sook Kim, Jin Young Yoon, Jin Ha Lee, Soung Min Jeon, Hyun Jung Bok, Jae Jun Park, Chang Mo Moon, Sung Pil Hong, Yong Chan Lee, Won Ho Kim

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Abstract

The purpose of this study is to evaluate the predictive capability of anorectal physiologic tests for unfavorable outcomes prior to the initiation of biofeedback therapy in patients with dyssynergic defecation. We analyzed a total of 80 consecutive patients who received biofeedback therapy for chronic idiopathic functional constipation with dyssynergic defecation. After classifying the patients into two groups (responders and non-responders), univariate and multivariate analyses were performed to determine the predictors associated with the responsiveness to biofeedback therapy. Of the 80 patients, 63 (78.7%) responded to biofeedback therapy and 17 (21.3%) did not. On univariate analysis, the inability to evacuate an intrarectal balloon (P=0.028), higher rectal volume for first, urgent, and maximal sensation (P=0.023, P=0.008, P=0.007, respectively), and increased anorectal angle during squeeze (P=0.020) were associated with poor outcomes. On multivariate analysis, the inability to evacuate an intrarectal balloon (P=0.018) and increased anorectal angle during squeeze (P=0.029) were both found to be independently associated with a lack of response to biofeedback therapy. Our data show that the two anorectal physiologic test factors are associated with poor response to biofeedback therapy for patients with dyssynergic defecation. These findings may assist physicians in predicting the responsiveness to therapy for this patient population.

Original languageEnglish
Pages (from-to)1060-1065
Number of pages6
JournalJournal of Korean medical science
Volume25
Issue number7
DOIs
Publication statusPublished - 2010 Jul

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Shin, J. K., Cheon, J. H., Kim, E. S., Yoon, J. Y., Lee, J. H., Jeon, S. M., Bok, H. J., Park, J. J., Moon, C. M., Hong, S. P., Lee, Y. C., & Kim, W. H. (2010). Predictive capability of anorectal physiologic tests for unfavorable outcomes following biofeedback therapy in dyssynergic defecation. Journal of Korean medical science, 25(7), 1060-1065. https://doi.org/10.3346/jkms.2010.25.7.1060