Predictors of kidney volume change and delayed kidney function recovery after donor nephrectomy

Hwang Gyun Jeon, Seung Ryeol Lee, Dong Jin Joo, Young Taik Oh, Myoung Soo Kim, YuSeun Kim, Seung Choul Yang, WoongKyu Han

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Purpose: To our knowledge the effects of preoperative kidney volume in living donors on the post-donation change in size and function of the remaining kidney have not been investigated. We studied the association between preoperative kidney volume, and volume change and delayed kidney function recovery in donors. Materials and Methods: From 2007 to 2008 we investigated 222 living donors. Kidney volume before and 6 months after surgery was estimated using the voxel count method. We analyzed correlations of kidney volume with patient characteristics, kidney function and actual kidney weight. To identify predictors of the volume increase of the remaining kidney and predictors of delayed kidney function recovery we performed regression analysis. Results: Mean ± SD total kidney volume was 311.9 ± 50.6 cc and it correlated with weight, body surface area and kidney function (p <0.001). The mean volume increase in the remaining kidney was 27.6% ± 9.7% (range 4.5% to 66.1%). Younger age (p <0.001) and lower preoperative volume of the remaining kidney (p = 0.019) were significant predictors of a greater increase in kidney volume on multiple linear regression analysis. Older age (OR 1.07, p <0.001), higher body mass index (OR 1.20, p = 0.008), lower preoperative kidney volume of the remaining kidney (OR 0.98, p = 0.003) and a lower preoperative diethylenetetramine pentaacetic acid glomerular filtration rate in the remaining kidney (OR 0.95, p = 0.017) were significant predictors of delayed kidney function recovery on multiple regression analysis. Conclusions: Kidney volume measured by the voxel count method was accurate and correlated with kidney function. Preoperative kidney volume is an independent predictor of the volume increase and delayed kidney function recovery in donors that could be used clinically.

Original languageEnglish
Pages (from-to)1057-1063
Number of pages7
JournalJournal of Urology
Volume184
Issue number3
DOIs
Publication statusPublished - 2010 Sep 1

Fingerprint

Recovery of Function
Nephrectomy
Tissue Donors
Kidney
Living Donors
Regression Analysis
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Urology
  • Medicine(all)

Cite this

Jeon, Hwang Gyun ; Lee, Seung Ryeol ; Joo, Dong Jin ; Oh, Young Taik ; Kim, Myoung Soo ; Kim, YuSeun ; Yang, Seung Choul ; Han, WoongKyu. / Predictors of kidney volume change and delayed kidney function recovery after donor nephrectomy. In: Journal of Urology. 2010 ; Vol. 184, No. 3. pp. 1057-1063.
@article{cc0273e287724a38a1928b7669548efd,
title = "Predictors of kidney volume change and delayed kidney function recovery after donor nephrectomy",
abstract = "Purpose: To our knowledge the effects of preoperative kidney volume in living donors on the post-donation change in size and function of the remaining kidney have not been investigated. We studied the association between preoperative kidney volume, and volume change and delayed kidney function recovery in donors. Materials and Methods: From 2007 to 2008 we investigated 222 living donors. Kidney volume before and 6 months after surgery was estimated using the voxel count method. We analyzed correlations of kidney volume with patient characteristics, kidney function and actual kidney weight. To identify predictors of the volume increase of the remaining kidney and predictors of delayed kidney function recovery we performed regression analysis. Results: Mean ± SD total kidney volume was 311.9 ± 50.6 cc and it correlated with weight, body surface area and kidney function (p <0.001). The mean volume increase in the remaining kidney was 27.6{\%} ± 9.7{\%} (range 4.5{\%} to 66.1{\%}). Younger age (p <0.001) and lower preoperative volume of the remaining kidney (p = 0.019) were significant predictors of a greater increase in kidney volume on multiple linear regression analysis. Older age (OR 1.07, p <0.001), higher body mass index (OR 1.20, p = 0.008), lower preoperative kidney volume of the remaining kidney (OR 0.98, p = 0.003) and a lower preoperative diethylenetetramine pentaacetic acid glomerular filtration rate in the remaining kidney (OR 0.95, p = 0.017) were significant predictors of delayed kidney function recovery on multiple regression analysis. Conclusions: Kidney volume measured by the voxel count method was accurate and correlated with kidney function. Preoperative kidney volume is an independent predictor of the volume increase and delayed kidney function recovery in donors that could be used clinically.",
author = "Jeon, {Hwang Gyun} and Lee, {Seung Ryeol} and Joo, {Dong Jin} and Oh, {Young Taik} and Kim, {Myoung Soo} and YuSeun Kim and Yang, {Seung Choul} and WoongKyu Han",
year = "2010",
month = "9",
day = "1",
doi = "10.1016/j.juro.2010.04.079",
language = "English",
volume = "184",
pages = "1057--1063",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "3",

}

Predictors of kidney volume change and delayed kidney function recovery after donor nephrectomy. / Jeon, Hwang Gyun; Lee, Seung Ryeol; Joo, Dong Jin; Oh, Young Taik; Kim, Myoung Soo; Kim, YuSeun; Yang, Seung Choul; Han, WoongKyu.

In: Journal of Urology, Vol. 184, No. 3, 01.09.2010, p. 1057-1063.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Predictors of kidney volume change and delayed kidney function recovery after donor nephrectomy

AU - Jeon, Hwang Gyun

AU - Lee, Seung Ryeol

AU - Joo, Dong Jin

AU - Oh, Young Taik

AU - Kim, Myoung Soo

AU - Kim, YuSeun

AU - Yang, Seung Choul

AU - Han, WoongKyu

PY - 2010/9/1

Y1 - 2010/9/1

N2 - Purpose: To our knowledge the effects of preoperative kidney volume in living donors on the post-donation change in size and function of the remaining kidney have not been investigated. We studied the association between preoperative kidney volume, and volume change and delayed kidney function recovery in donors. Materials and Methods: From 2007 to 2008 we investigated 222 living donors. Kidney volume before and 6 months after surgery was estimated using the voxel count method. We analyzed correlations of kidney volume with patient characteristics, kidney function and actual kidney weight. To identify predictors of the volume increase of the remaining kidney and predictors of delayed kidney function recovery we performed regression analysis. Results: Mean ± SD total kidney volume was 311.9 ± 50.6 cc and it correlated with weight, body surface area and kidney function (p <0.001). The mean volume increase in the remaining kidney was 27.6% ± 9.7% (range 4.5% to 66.1%). Younger age (p <0.001) and lower preoperative volume of the remaining kidney (p = 0.019) were significant predictors of a greater increase in kidney volume on multiple linear regression analysis. Older age (OR 1.07, p <0.001), higher body mass index (OR 1.20, p = 0.008), lower preoperative kidney volume of the remaining kidney (OR 0.98, p = 0.003) and a lower preoperative diethylenetetramine pentaacetic acid glomerular filtration rate in the remaining kidney (OR 0.95, p = 0.017) were significant predictors of delayed kidney function recovery on multiple regression analysis. Conclusions: Kidney volume measured by the voxel count method was accurate and correlated with kidney function. Preoperative kidney volume is an independent predictor of the volume increase and delayed kidney function recovery in donors that could be used clinically.

AB - Purpose: To our knowledge the effects of preoperative kidney volume in living donors on the post-donation change in size and function of the remaining kidney have not been investigated. We studied the association between preoperative kidney volume, and volume change and delayed kidney function recovery in donors. Materials and Methods: From 2007 to 2008 we investigated 222 living donors. Kidney volume before and 6 months after surgery was estimated using the voxel count method. We analyzed correlations of kidney volume with patient characteristics, kidney function and actual kidney weight. To identify predictors of the volume increase of the remaining kidney and predictors of delayed kidney function recovery we performed regression analysis. Results: Mean ± SD total kidney volume was 311.9 ± 50.6 cc and it correlated with weight, body surface area and kidney function (p <0.001). The mean volume increase in the remaining kidney was 27.6% ± 9.7% (range 4.5% to 66.1%). Younger age (p <0.001) and lower preoperative volume of the remaining kidney (p = 0.019) were significant predictors of a greater increase in kidney volume on multiple linear regression analysis. Older age (OR 1.07, p <0.001), higher body mass index (OR 1.20, p = 0.008), lower preoperative kidney volume of the remaining kidney (OR 0.98, p = 0.003) and a lower preoperative diethylenetetramine pentaacetic acid glomerular filtration rate in the remaining kidney (OR 0.95, p = 0.017) were significant predictors of delayed kidney function recovery on multiple regression analysis. Conclusions: Kidney volume measured by the voxel count method was accurate and correlated with kidney function. Preoperative kidney volume is an independent predictor of the volume increase and delayed kidney function recovery in donors that could be used clinically.

UR - http://www.scopus.com/inward/record.url?scp=77956631927&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77956631927&partnerID=8YFLogxK

U2 - 10.1016/j.juro.2010.04.079

DO - 10.1016/j.juro.2010.04.079

M3 - Article

VL - 184

SP - 1057

EP - 1063

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 3

ER -