Abstract
Neuroblastoma is the most common pediatric extracranial solid tumor derived from primitive neural crest cells of the sympathetic nervous system. Although one-fifths of all neuroblastomas occurs within the thorax, thoracic neuroblastomas detected in fetus have been rarely reported. We report a case of fetal thoracic neuroblastoma with massive pleural effusion detected with prenatal ultrasonography. A 34-year-old Korean second-gravida was referred to our hospital at 30 weeks of gestation for evaluation, after the right lung mass found in the fetus. Approximately 3 cm, well-defined, hyperechoic mass was found in the right thorax with right pleural effusion, with the initial suspicion of teratoma. However, as mass continued to grow with deteriorating pleural effusion and fetal hydrops, the mass was considered malignant after 3 weeks. After a cesarean delivery, an approximately 4 cm mass with peripheral calcification and hemothorax was found on neonatal ultrasonography. Neuroblastoma was diagnosed on excision biopsy.
| Original language | English |
|---|---|
| Pages (from-to) | 278-281 |
| Number of pages | 4 |
| Journal | Obstetrics and Gynecology Science |
| Volume | 61 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2018 Mar 1 |
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All Science Journal Classification (ASJC) codes
- Obstetrics and Gynaecology
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Prenatally detected thoracic neuroblastoma. / Park, Yejin; Lee, Hyun Jin; Jung, Yun Ji; Lee, Joon Ho; Kwon, Ja Young; Kim, Young Han.
In: Obstetrics and Gynecology Science, Vol. 61, No. 2, 01.03.2018, p. 278-281.Research output: Contribution to journal › Article
TY - JOUR
T1 - Prenatally detected thoracic neuroblastoma
AU - Park, Yejin
AU - Lee, Hyun Jin
AU - Jung, Yun Ji
AU - Lee, Joon Ho
AU - Kwon, Ja Young
AU - Kim, Young Han
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Neuroblastoma is the most common pediatric extracranial solid tumor derived from primitive neural crest cells of the sympathetic nervous system. Although one-fifths of all neuroblastomas occurs within the thorax, thoracic neuroblastomas detected in fetus have been rarely reported. We report a case of fetal thoracic neuroblastoma with massive pleural effusion detected with prenatal ultrasonography. A 34-year-old Korean second-gravida was referred to our hospital at 30 weeks of gestation for evaluation, after the right lung mass found in the fetus. Approximately 3 cm, well-defined, hyperechoic mass was found in the right thorax with right pleural effusion, with the initial suspicion of teratoma. However, as mass continued to grow with deteriorating pleural effusion and fetal hydrops, the mass was considered malignant after 3 weeks. After a cesarean delivery, an approximately 4 cm mass with peripheral calcification and hemothorax was found on neonatal ultrasonography. Neuroblastoma was diagnosed on excision biopsy.
AB - Neuroblastoma is the most common pediatric extracranial solid tumor derived from primitive neural crest cells of the sympathetic nervous system. Although one-fifths of all neuroblastomas occurs within the thorax, thoracic neuroblastomas detected in fetus have been rarely reported. We report a case of fetal thoracic neuroblastoma with massive pleural effusion detected with prenatal ultrasonography. A 34-year-old Korean second-gravida was referred to our hospital at 30 weeks of gestation for evaluation, after the right lung mass found in the fetus. Approximately 3 cm, well-defined, hyperechoic mass was found in the right thorax with right pleural effusion, with the initial suspicion of teratoma. However, as mass continued to grow with deteriorating pleural effusion and fetal hydrops, the mass was considered malignant after 3 weeks. After a cesarean delivery, an approximately 4 cm mass with peripheral calcification and hemothorax was found on neonatal ultrasonography. Neuroblastoma was diagnosed on excision biopsy.
UR - http://www.scopus.com/inward/record.url?scp=85043978548&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85043978548&partnerID=8YFLogxK
U2 - 10.5468/ogs.2018.61.2.278
DO - 10.5468/ogs.2018.61.2.278
M3 - Article
AN - SCOPUS:85043978548
VL - 61
SP - 278
EP - 281
JO - Obstetrics and Gynecology Science
JF - Obstetrics and Gynecology Science
SN - 2287-8572
IS - 2
ER -