Preoperative clinical features of reactivated of Graves' orbitopathy after orbital decompression

Y. J. Woo, J. W. Kim, J. S. Yoon

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose To investigate the incidence and preoperative clinical features of reactivated Graves' orbitopathy (GO) after orbital decompression.MethodsThis study included patients with GO who underwent orbital decompression for disfiguring proptosis and not compressive optic neuropathy and received postoperative follow-up care for more than 12 months. Patients who experienced active inflammatory signs within 6 months of decompression were excluded from analysis. The demographic characteristics, ophthalmic manifestations, and biochemical parameters of the patients were analyzed for association with reactivation of GO by logistic regression analysis.ResultsOut of the 92 patients included in this study, seven (7.6%) experienced reactivation of GO after orbital decompression. The mean time interval between surgery and reactivation of GO was 36.3±14.3 weeks. Univariate logistic regression analysis identified age, existing smoking habits, and modified NOSPECS and Gorman scores as significant factors for the reactivation of GO. The results of multivariate logistic regression analysis revealed that smoking and modified NOSPECS and Gorman scores were associated with the reactivation of GO.ConclusionsQuitting smoking is important for the prevention of reactivation of GO after orbital decompression. Patients with severe symptoms, especially those with restrictive myopathy, should be carefully monitored for reactivation of GO after orbital decompression.

Original languageEnglish
Pages (from-to)643-649
Number of pages7
JournalEye (Basingstoke)
Volume31
Issue number4
DOIs
Publication statusPublished - 2017 Apr 1

Fingerprint

Decompression
Logistic Models
Smoking
Regression Analysis
Eye Manifestations
Optic Nerve Diseases
Aftercare
Exophthalmos
Muscular Diseases
Habits
Demography
Incidence

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems

Cite this

@article{2abc461f042c4ff1a3b00f5334eb590a,
title = "Preoperative clinical features of reactivated of Graves' orbitopathy after orbital decompression",
abstract = "Purpose To investigate the incidence and preoperative clinical features of reactivated Graves' orbitopathy (GO) after orbital decompression.MethodsThis study included patients with GO who underwent orbital decompression for disfiguring proptosis and not compressive optic neuropathy and received postoperative follow-up care for more than 12 months. Patients who experienced active inflammatory signs within 6 months of decompression were excluded from analysis. The demographic characteristics, ophthalmic manifestations, and biochemical parameters of the patients were analyzed for association with reactivation of GO by logistic regression analysis.ResultsOut of the 92 patients included in this study, seven (7.6{\%}) experienced reactivation of GO after orbital decompression. The mean time interval between surgery and reactivation of GO was 36.3±14.3 weeks. Univariate logistic regression analysis identified age, existing smoking habits, and modified NOSPECS and Gorman scores as significant factors for the reactivation of GO. The results of multivariate logistic regression analysis revealed that smoking and modified NOSPECS and Gorman scores were associated with the reactivation of GO.ConclusionsQuitting smoking is important for the prevention of reactivation of GO after orbital decompression. Patients with severe symptoms, especially those with restrictive myopathy, should be carefully monitored for reactivation of GO after orbital decompression.",
author = "Woo, {Y. J.} and Kim, {J. W.} and Yoon, {J. S.}",
year = "2017",
month = "4",
day = "1",
doi = "10.1038/eye.2016.304",
language = "English",
volume = "31",
pages = "643--649",
journal = "Eye",
issn = "0950-222X",
publisher = "Nature Publishing Group",
number = "4",

}

Preoperative clinical features of reactivated of Graves' orbitopathy after orbital decompression. / Woo, Y. J.; Kim, J. W.; Yoon, J. S.

In: Eye (Basingstoke), Vol. 31, No. 4, 01.04.2017, p. 643-649.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Preoperative clinical features of reactivated of Graves' orbitopathy after orbital decompression

AU - Woo, Y. J.

AU - Kim, J. W.

AU - Yoon, J. S.

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Purpose To investigate the incidence and preoperative clinical features of reactivated Graves' orbitopathy (GO) after orbital decompression.MethodsThis study included patients with GO who underwent orbital decompression for disfiguring proptosis and not compressive optic neuropathy and received postoperative follow-up care for more than 12 months. Patients who experienced active inflammatory signs within 6 months of decompression were excluded from analysis. The demographic characteristics, ophthalmic manifestations, and biochemical parameters of the patients were analyzed for association with reactivation of GO by logistic regression analysis.ResultsOut of the 92 patients included in this study, seven (7.6%) experienced reactivation of GO after orbital decompression. The mean time interval between surgery and reactivation of GO was 36.3±14.3 weeks. Univariate logistic regression analysis identified age, existing smoking habits, and modified NOSPECS and Gorman scores as significant factors for the reactivation of GO. The results of multivariate logistic regression analysis revealed that smoking and modified NOSPECS and Gorman scores were associated with the reactivation of GO.ConclusionsQuitting smoking is important for the prevention of reactivation of GO after orbital decompression. Patients with severe symptoms, especially those with restrictive myopathy, should be carefully monitored for reactivation of GO after orbital decompression.

AB - Purpose To investigate the incidence and preoperative clinical features of reactivated Graves' orbitopathy (GO) after orbital decompression.MethodsThis study included patients with GO who underwent orbital decompression for disfiguring proptosis and not compressive optic neuropathy and received postoperative follow-up care for more than 12 months. Patients who experienced active inflammatory signs within 6 months of decompression were excluded from analysis. The demographic characteristics, ophthalmic manifestations, and biochemical parameters of the patients were analyzed for association with reactivation of GO by logistic regression analysis.ResultsOut of the 92 patients included in this study, seven (7.6%) experienced reactivation of GO after orbital decompression. The mean time interval between surgery and reactivation of GO was 36.3±14.3 weeks. Univariate logistic regression analysis identified age, existing smoking habits, and modified NOSPECS and Gorman scores as significant factors for the reactivation of GO. The results of multivariate logistic regression analysis revealed that smoking and modified NOSPECS and Gorman scores were associated with the reactivation of GO.ConclusionsQuitting smoking is important for the prevention of reactivation of GO after orbital decompression. Patients with severe symptoms, especially those with restrictive myopathy, should be carefully monitored for reactivation of GO after orbital decompression.

UR - http://www.scopus.com/inward/record.url?scp=85017461945&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85017461945&partnerID=8YFLogxK

U2 - 10.1038/eye.2016.304

DO - 10.1038/eye.2016.304

M3 - Article

C2 - 28060361

AN - SCOPUS:85017461945

VL - 31

SP - 643

EP - 649

JO - Eye

JF - Eye

SN - 0950-222X

IS - 4

ER -