Preoperative imaging of sentinel lymph nodes in gastric cancer using CT lymphography

Woo Jin Hyung, Yong Soo Kim, Joon Seok Lim, Myeong Jin Kim, Sung Hoon Noh, Ki Whang Kim

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: Preoperative identification of the sentinel lymph node (SLN) in gastric cancer (GC) patients may have great advantages for the minimally invasive treatment. This study was performed to evaluate the possibility of preoperative SLN detection using CT lymphography. Materials and Methods: Fourteen patients with early GC were enrolled. CT images were obtained before and at 1, 3, and 5 minutes after endoscopic submucosal peritumoral injection of 2 mL iopamidol. For patients with clearly identified SLNs, to make comparisons with the CT lymphography results, intraoperative SLN detection was performed using subserosally injected Indocyanine green (ICG) lymphography and ex vivo ICG and iopamidol lymphography using mammography was also performed. Results: CT lymphography clearly visualized draining lymphatics and SLNs in 4 (28.6%) out of 14 patients. All clearly visualized SLNs (one to three SLNs per patient) under preoperative imaging were detected in the same location by intraoperative ICG lymphography and ex vivo ICG and iopamidol lymphography using mammography. All preoperative SLN detections were observed with the primary tumors in the lower third of the stomach. Conclusion: Although our study demonstrated a SLN detection rate of less than 30%, CT lymphography with radio-contrast showed potential as a method of preoperative SLN detection for GC.

Original languageEnglish
Pages (from-to)407-413
Number of pages7
JournalYonsei medical journal
Volume51
Issue number3
DOIs
Publication statusPublished - 2010 May 1

Fingerprint

Lymphography
Stomach Neoplasms
Indocyanine Green
Iopamidol
Mammography
Sentinel Lymph Node
Radio
Stomach
Injections

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Hyung, Woo Jin ; Kim, Yong Soo ; Lim, Joon Seok ; Kim, Myeong Jin ; Noh, Sung Hoon ; Kim, Ki Whang. / Preoperative imaging of sentinel lymph nodes in gastric cancer using CT lymphography. In: Yonsei medical journal. 2010 ; Vol. 51, No. 3. pp. 407-413.
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abstract = "Purpose: Preoperative identification of the sentinel lymph node (SLN) in gastric cancer (GC) patients may have great advantages for the minimally invasive treatment. This study was performed to evaluate the possibility of preoperative SLN detection using CT lymphography. Materials and Methods: Fourteen patients with early GC were enrolled. CT images were obtained before and at 1, 3, and 5 minutes after endoscopic submucosal peritumoral injection of 2 mL iopamidol. For patients with clearly identified SLNs, to make comparisons with the CT lymphography results, intraoperative SLN detection was performed using subserosally injected Indocyanine green (ICG) lymphography and ex vivo ICG and iopamidol lymphography using mammography was also performed. Results: CT lymphography clearly visualized draining lymphatics and SLNs in 4 (28.6{\%}) out of 14 patients. All clearly visualized SLNs (one to three SLNs per patient) under preoperative imaging were detected in the same location by intraoperative ICG lymphography and ex vivo ICG and iopamidol lymphography using mammography. All preoperative SLN detections were observed with the primary tumors in the lower third of the stomach. Conclusion: Although our study demonstrated a SLN detection rate of less than 30{\%}, CT lymphography with radio-contrast showed potential as a method of preoperative SLN detection for GC.",
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Preoperative imaging of sentinel lymph nodes in gastric cancer using CT lymphography. / Hyung, Woo Jin; Kim, Yong Soo; Lim, Joon Seok; Kim, Myeong Jin; Noh, Sung Hoon; Kim, Ki Whang.

In: Yonsei medical journal, Vol. 51, No. 3, 01.05.2010, p. 407-413.

Research output: Contribution to journalArticle

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