Preparation and characterization of PEG/PLA multiblock and triblock copolymer

Hesong Zhao, Zhun Liu, Sanghyuk Park, Sang Ho Kim, Jung-Hyun Kim, Longhai Piao

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A series of poly (lactic acid) (PLA) and poly (ethylene glycol) (PEG) tri and multiblock copolymers with relatively high molecular weights were synthesized through the coupling reaction between the bis(acyl chloride) of carboxylated PLA and mono or dihydroxy PEG. The coupling reaction and the copolymer structures were monitored by nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FTIR) and gel permeation chromatography (GPC). The melting temperature (Tm) of PEG blocks decreased with the presence of PLA sequences attaching to PEG blocks. The CMC values were determined to be 10-145 mg/L depending on the length of PLA and PEG blocks and the structure of the block copolymers.

Original languageEnglish
Pages (from-to)1638-1642
Number of pages5
JournalBulletin of the Korean Chemical Society
Volume33
Issue number5
DOIs
Publication statusPublished - 2012 May 20

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Polyethylene glycols
Block copolymers
Copolymers
Gel permeation chromatography
Melting point
Chlorides
Molecular weight
Nuclear magnetic resonance

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Zhao, Hesong ; Liu, Zhun ; Park, Sanghyuk ; Kim, Sang Ho ; Kim, Jung-Hyun ; Piao, Longhai. / Preparation and characterization of PEG/PLA multiblock and triblock copolymer. In: Bulletin of the Korean Chemical Society. 2012 ; Vol. 33, No. 5. pp. 1638-1642.
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Preparation and characterization of PEG/PLA multiblock and triblock copolymer. / Zhao, Hesong; Liu, Zhun; Park, Sanghyuk; Kim, Sang Ho; Kim, Jung-Hyun; Piao, Longhai.

In: Bulletin of the Korean Chemical Society, Vol. 33, No. 5, 20.05.2012, p. 1638-1642.

Research output: Contribution to journalArticle

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