Preparation of uniform microspheres using a simple fluidic device and their crystallization into close-packed lattices

Sung Wook Choi, In Woo Cheong, Jung-Hyun Kim, Younan Xia

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

The preparation of uniform raspberry-like microspheres using a simple fluidics device and their crystallization into close-packed lattices was investigated. The spheres was developed by stable Oil-in-Water (O/W) or Water-in-Oil (W/O) emulsions and scanning Electron Microscopy (SEM) of close packed lattices was done. Various types of microfluidic devices have been developed to generate microparticles with diverse morphologies such as spheres, rods, disks and ellipsoids. The device provided precise control over the formation of emulsion droplets, leading to the production of uniform microspheres in size ranging from 30 to 250 μm. The technique provided a powerful strategy for the scalable and continuous production of microspheres from both organic and inorganic materials actively sought for encapsulation of drugs, dyes, and tissue engineering.

Original languageEnglish
Pages (from-to)454-459
Number of pages6
JournalSmall
Volume5
Issue number4
DOIs
Publication statusPublished - 2009 Feb 20

Fingerprint

Fluidic devices
Crystallization
Microspheres
Crystal lattices
Lab-On-A-Chip Devices
Emulsions
Equipment and Supplies
Oils
Water
Tissue Engineering
Encapsulation
Tissue engineering
Microfluidics
Electron Scanning Microscopy
Coloring Agents
Dyes
Scanning electron microscopy
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomaterials
  • Engineering (miscellaneous)

Cite this

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Preparation of uniform microspheres using a simple fluidic device and their crystallization into close-packed lattices. / Choi, Sung Wook; Cheong, In Woo; Kim, Jung-Hyun; Xia, Younan.

In: Small, Vol. 5, No. 4, 20.02.2009, p. 454-459.

Research output: Contribution to journalArticle

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