Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli

Yeon Joon Park, Jin Kyung Yu, Kang Gyun Park, Yong Gyu Park, Seongok Lee, Soo Young Kim, Seokhoon Jeong

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Among the extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae and Escherichia coli, 3.9% of K. pneumoniae showed nonsusceptibility to imipenem or meropenem; and their mechanism was the combination of ESBL and/or plasmid-mediated AmpC β-lactamase production and porin loss. The presence of bla CTX-M-14 and loss of OmpK36 were associated with higher carbapenem MICs.

Original languageEnglish
Pages (from-to)87-89
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume71
Issue number1
DOIs
Publication statusPublished - 2011 Sep 1

Fingerprint

meropenem
Imipenem
Klebsiella pneumoniae
Escherichia coli
Porins
Carbapenems
Plasmids

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

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abstract = "Among the extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae and Escherichia coli, 3.9{\%} of K. pneumoniae showed nonsusceptibility to imipenem or meropenem; and their mechanism was the combination of ESBL and/or plasmid-mediated AmpC β-lactamase production and porin loss. The presence of bla CTX-M-14 and loss of OmpK36 were associated with higher carbapenem MICs.",
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Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli. / Park, Yeon Joon; Yu, Jin Kyung; Park, Kang Gyun; Park, Yong Gyu; Lee, Seongok; Kim, Soo Young; Jeong, Seokhoon.

In: Diagnostic Microbiology and Infectious Disease, Vol. 71, No. 1, 01.09.2011, p. 87-89.

Research output: Contribution to journalArticle

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AU - Kim, Soo Young

AU - Jeong, Seokhoon

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