Among the extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae and Escherichia coli, 3.9% of K. pneumoniae showed nonsusceptibility to imipenem or meropenem; and their mechanism was the combination of ESBL and/or plasmid-mediated AmpC β-lactamase production and porin loss. The presence of bla CTX-M-14 and loss of OmpK36 were associated with higher carbapenem MICs.
|Number of pages||3|
|Journal||Diagnostic Microbiology and Infectious Disease|
|Publication status||Published - 2011 Sep|
Bibliographical noteFunding Information:
We wish to thank all the contributing laboratories that provided isolates for this study. This work was supported by a research grant from the Korea Center for Disease Control (2009-E00520-00).
All Science Journal Classification (ASJC) codes
- Microbiology (medical)
- Infectious Diseases